2s
The (most) everything API: 575+ pay-per-call endpoints for AI agents — ground-truth data, a full AI gateway, and agent infrastructure (storage, queues, watchers). USDC via x402, no signup, no API keys, and upto billing: pay actual usage, not the quote.
The wallet the 402 directs payment to. Its whole payment record — every payer, every chain — is on the merchant page.
Asset 0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913
The payTo wallet does not resolve to a registered ERC-8004 agent. That is not a verdict on the service — most of the catalog is unregistered.
Live 402 challenge
Captured by the enrichment pass, not read just now. Prices can change — always read the 402 the endpoint answers with.
{
"error": "PAYMENT-SIGNATURE required",
"accepts": [
{
"asset": "0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913",
"extra": {
"name": "USD Coin",
"version": "2"
},
"payTo": "0x2b6D4988Db4723E6908Db86Ab2b8dFBc51FC32C5",
"amount": "3000",
"scheme": "exact",
"network": "eip155:8453",
"maxTimeoutSeconds": 60
},
{
"asset": "EPjFWdd5AufqSSqeM2qN1xzybapC8G4wEGGkZwyTDt1v",
"extra": {
"name": "USDC",
"version": "1",
"feePayer": "GVJJ7rdGiXr5xaYbRwRbjfaJL7fmwRygFi1H6aGqDveb"
},
"payTo": "TW6ntaGzvj63ZgPjszd4FCGmVTGfzv1MAYZbjYcyWhn",
"amount": "3000",
"scheme": "exact",
"network": "solana:5eykt4UsFv8P8NJdTREpY1vzqKqZKvdp",
"maxTimeoutSeconds": 60
}
],
"resource": {
"url": "https://2s.io/api/clinical/trial-search",
"tags": [
"public-records",
"identifiers",
"ai-agents",
"us-gov-data",
"x402",
"upto-billing",
"ai-gateway",
"agent-infrastructure"
],
"iconUrl": "https://2s.io/icon-512.png",
"mimeType": "application/json",
"description": "Search ClinicalTrials.gov — every registered US (and many international) clinical study (~500k trials). Free-text query matches title + condition + intervention; or direct lookup by NCT ID. Optional filters: recruitment status, lead sponsor, phase (PHASE1..PHASE4), country. Each record includes NCT ID, brief + official title, status, phases, study type, conditions list, interventions (with type + name), enrollment count + type, key dates (start / primary completion / completion / first posted / last update), lead sponsor + class (INDUSTRY/NIH/OTHER), hasResults flag, brief summary, and canonical clinicaltrials.gov URL. Public-domain NIH NLM data.",
"serviceName": "2s"
},
"extensions": {
"bazaar": {
"info": {
"input": {
"type": "http",
"method": "GET",
"queryParams": {
"query": "mRNA vaccine",
"status": "RECRUITING",
"pageSize": 3
}
},
"output": {
"type": "json",
"schema": {
"type": "object",
"properties": {
"ok": {
"type": "boolean"
},
"meta": {
"type": "object",
"properties": {
"query": {
"type": "object",
"properties": {
"nctId": {},
"phase": {},
"query": {
"type": "string"
},
"status": {
"type": "string"
},
"country": {},
"sponsor": {},
"pageSize": {
"type": "integer"
}
}
},
"nextPageToken": {
"type": "string"
}
}
},
"items": {
"type": "array",
"items": {
"type": "object",
"properties": {
"url": {
"type": "string"
},
"nctId": {
"type": "string"
},
"phases": {
"type": "array",
"items": {
"type": "string"
}
},
"status": {
"type": "string"
},
"startDate": {
"type": "string"
},
"studyType": {
"type": "string"
},
"briefTitle": {
"type": "string"
},
"conditions": {
"type": "array",
"items": {
"type": "string"
}
},
"hasResults": {
"type": "boolean"
},
"leadSponsor": {
"type": "string"
},
"briefSummary": {
"type": "string"
},
"interventions": {
"type": "array",
"items": {
"type": "object",
"properties": {
"name": {
"type": "string"
},
"type": {
"type": "string"
}
}
}
},
"officialTitle": {},
"completionDate": {
"type": "string"
},
"enrollmentType": {
"type": "string"
},
"enrollmentCount": {
"type": "integer"
},
"leadSponsorClass": {
"type": "string"
},
"lastUpdatePostedDate": {
"type": "string"
},
"studyFirstPostedDate": {
"type": "string"
},
"primaryCompletionDate": {
"type": "string"
}
}
}
},
"total": {},
"source": {
"type": "object",
"properties": {
"url": {
"type": "string"
},
"license": {
"type": "string"
},
"provider": {
"type": "string"
}
}
}
}
},
"example": {
"ok": true,
"meta": {
"query": {
"nctId": null,
"phase": null,
"query": "mRNA vaccine",
"status": "RECRUITING",
"country": null,
"sponsor": null,
"pageSize": 3
},
"nextPageToken": "NF1xy0o"
},
"items": [
{
"url": "https://clinicaltrials.gov/study/NCT06000000",
"nctId": "NCT06000000",
"phases": [
"PHASE1"
],
"status": "RECRUITING",
"startDate": "2024-09-01",
"studyType": "INTERVENTIONAL",
"briefTitle": "mRNA Vaccine for Pancreatic Cancer",
"conditions": [
"Pancreatic Cancer"
],
"hasResults": false,
"leadSponsor": "Memorial Sloan Kettering Cancer Center",
"briefSummary": "Phase I trial evaluating safety and tolerability of a personalized mRNA vaccine...",
"interventions": [
{
"name": "BNT-122",
"type": "BIOLOGICAL"
}
],
"officialTitle": null,
"completionDate": "2029-06-01",
"enrollmentType": "ESTIMATED",
"enrollmentCount": 60,
"leadSponsorClass": "OTHER",
"lastUpdatePostedDate": "2026-05-20",
"studyFirstPostedDate": "2024-08-15",
"primaryCompletionDate": "2027-06-01"
}
],
"total": null,
"source": {
"url": "https://clinicaltrials.gov/",
"license": "Public domain (US government work)",
"provider": "ClinicalTrials.gov (NIH National Library of Medicine)"
}
}
}
},
"schema": {
"type": "object",
"$schema": "https://json-schema.org/draft/2020-12/schema",
"required": [
"input"
],
"properties": {
"input": {
"type": "object",
"required": [
"type",
"method",
"queryParams"
],
"properties": {
"type": {
"const": "http"
},
"method": {
"const": "GET"
},
"queryParams": {
"properties": {
"nctId": {
"type": "string",
"description": "Direct NCT ID lookup (NCT\\d{8})."
},
"phase": {
"type": "string",
"description": "PHASE1 | PHASE2 | PHASE3 | PHASE4 | NA | EARLY_PHASE1."
},
"query": {
"type": "string",
"description": "Free-text query (title/condition/intervention/sponsor)."
},
"status": {
"enum": [
"RECRUITING",
"ACTIVE_NOT_RECRUITING",
"COMPLETED",
"TERMINATED",
"WITHDRAWN",
"NOT_YET_RECRUITING",
"SUSPENDED"
],
"type": "string"
},
"country": {
"type": "string",
"description": "Country name (e.g., \"United States\")."
},
"sponsor": {
"type": "string",
"description": "Lead sponsor name filter."
},
"pageSize": {
"type": "integer",
"default": 10,
"maximum": 100,
"minimum": 1
},
"pageToken": {
"type": "string",
"description": "Opaque token from prior response (pagination)."
}
}
}
}
},
"output": {
"type": "object",
"properties": {
"ok": {
"type": "boolean"
},
"meta": {
"type": "object",
"properties": {
"query": {
"type": "object",
"properties": {
"nctId": {},
"phase": {},
"query": {
"type": "string"
},
"status": {
"type": "string"
},
"country": {},
"sponsor": {},
"pageSize": {
"type": "integer"
}
}
},
"nextPageToken": {
"type": "string"
}
}
},
"items": {
"type": "array",
"items": {
"type": "object",
"properties": {
"url": {
"type": "string"
},
"nctId": {
"type": "string"
},
"phases": {
"type": "array",
"items": {
"type": "string"
}
},
"status": {
"type": "string"
},
"startDate": {
"type": "string"
},
"studyType": {
"type": "string"
},
"briefTitle": {
"type": "string"
},
"conditions": {
"type": "array",
"items": {
"type": "string"
}
},
"hasResults": {
"type": "boolean"
},
"leadSponsor": {
"type": "string"
},
"briefSummary": {
"type": "string"
},
"interventions": {
"type": "array",
"items": {
"type": "object",
"properties": {
"name": {
"type": "string"
},
"type": {
"type": "string"
}
}
}
},
"officialTitle": {},
"completionDate": {
"type": "string"
},
"enrollmentType": {
"type": "string"
},
"enrollmentCount": {
"type": "integer"
},
"leadSponsorClass": {
"type": "string"
},
"lastUpdatePostedDate": {
"type": "string"
},
"studyFirstPostedDate": {
"type": "string"
},
"primaryCompletionDate": {
"type": "string"
}
}
}
},
"total": {},
"source": {
"type": "object",
"properties": {
"url": {
"type": "string"
},
"license": {
"type": "string"
},
"provider": {
"type": "string"
}
}
}
}
}
}
}
}
},
"x402Version": 2
}Accepts
The payment requirements as published to the catalog. Read the live 402 before paying — a price here is a claim, not a quote.
Pay 0.0012 USDC on Base to 0x2b6D…C32C5. The signed payment is good for 1 minute.
- Paid to
- 0x2b6D…C32C5
- USD Coin contract
- 0x8335…02913
- Payment window
- 1 minute
- As published
- 1200 smallest units
That figure is in the token’s smallest units. Roundhouse does not hold this contract’s decimals, so it is shown as published rather than converted.
- Paid to
- TW6nta…cyWhn
- Token contract
- EPjFWd…TDt1v
- Payment window
- 1 minute
The catalog’s raw entry
[
{
"asset": "0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913",
"extra": {
"name": "USD Coin",
"version": "2"
},
"payTo": "0x2b6D4988Db4723E6908Db86Ab2b8dFBc51FC32C5",
"amount": "1200",
"scheme": "exact",
"network": "eip155:8453",
"maxTimeoutSeconds": 60
},
{
"asset": "EPjFWdd5AufqSSqeM2qN1xzybapC8G4wEGGkZwyTDt1v",
"extra": {
"name": "USDC",
"version": "1",
"feePayer": "BFK9TLC3edb13K6v4YyH3DwPb5DSUpkWvb7XnqCL9b4F"
},
"payTo": "TW6ntaGzvj63ZgPjszd4FCGmVTGfzv1MAYZbjYcyWhn",
"amount": "1200",
"scheme": "exact",
"network": "solana:5eykt4UsFv8P8NJdTREpY1vzqKqZKvdp",
"maxTimeoutSeconds": 60
}
]Extensions
{
"bazaar": {
"info": {
"input": {
"type": "http",
"method": "GET",
"queryParams": {
"query": "mRNA vaccine",
"status": "RECRUITING",
"pageSize": 3
}
},
"output": {
"type": "json",
"schema": {
"type": "object",
"properties": {
"ok": {
"type": "boolean"
},
"meta": {
"type": "object",
"properties": {
"query": {
"type": "object",
"properties": {
"nctId": {},
"phase": {},
"query": {
"type": "string"
},
"status": {
"type": "string"
},
"country": {},
"sponsor": {},
"pageSize": {
"type": "integer"
}
}
},
"nextPageToken": {
"type": "string"
}
}
},
"items": {
"type": "array",
"items": {
"type": "object",
"properties": {
"url": {
"type": "string"
},
"nctId": {
"type": "string"
},
"phases": {
"type": "array",
"items": {
"type": "string"
}
},
"status": {
"type": "string"
},
"startDate": {
"type": "string"
},
"studyType": {
"type": "string"
},
"briefTitle": {
"type": "string"
},
"conditions": {
"type": "array",
"items": {
"type": "string"
}
},
"hasResults": {
"type": "boolean"
},
"leadSponsor": {
"type": "string"
},
"briefSummary": {
"type": "string"
},
"interventions": {
"type": "array",
"items": {
"type": "object",
"properties": {
"name": {
"type": "string"
},
"type": {
"type": "string"
}
}
}
},
"officialTitle": {},
"completionDate": {
"type": "string"
},
"enrollmentType": {
"type": "string"
},
"enrollmentCount": {
"type": "integer"
},
"leadSponsorClass": {
"type": "string"
},
"lastUpdatePostedDate": {
"type": "string"
},
"studyFirstPostedDate": {
"type": "string"
},
"primaryCompletionDate": {
"type": "string"
}
}
}
},
"total": {},
"source": {
"type": "object",
"properties": {
"url": {
"type": "string"
},
"license": {
"type": "string"
},
"provider": {
"type": "string"
}
}
}
}
},
"example": {
"ok": true,
"meta": {
"query": {
"nctId": null,
"phase": null,
"query": "mRNA vaccine",
"status": "RECRUITING",
"country": null,
"sponsor": null,
"pageSize": 3
},
"nextPageToken": "NF1xy0o"
},
"items": [
{
"url": "https://clinicaltrials.gov/study/NCT06000000",
"nctId": "NCT06000000",
"phases": [
"PHASE1"
],
"status": "RECRUITING",
"startDate": "2024-09-01",
"studyType": "INTERVENTIONAL",
"briefTitle": "mRNA Vaccine for Pancreatic Cancer",
"conditions": [
"Pancreatic Cancer"
],
"hasResults": false,
"leadSponsor": "Memorial Sloan Kettering Cancer Center",
"briefSummary": "Phase I trial evaluating safety and tolerability of a personalized mRNA vaccine...",
"interventions": [
{
"name": "BNT-122",
"type": "BIOLOGICAL"
}
],
"officialTitle": null,
"completionDate": "2029-06-01",
"enrollmentType": "ESTIMATED",
"enrollmentCount": 60,
"leadSponsorClass": "OTHER",
"lastUpdatePostedDate": "2026-05-20",
"studyFirstPostedDate": "2024-08-15",
"primaryCompletionDate": "2027-06-01"
}
],
"total": null,
"source": {
"url": "https://clinicaltrials.gov/",
"license": "Public domain (US government work)",
"provider": "ClinicalTrials.gov (NIH National Library of Medicine)"
}
}
}
},
"schema": {
"type": "object",
"$schema": "https://json-schema.org/draft/2020-12/schema",
"required": [
"input"
],
"properties": {
"input": {
"type": "object",
"required": [
"type",
"method",
"queryParams"
],
"properties": {
"type": {
"const": "http"
},
"method": {
"const": "GET"
},
"queryParams": {
"properties": {
"nctId": {
"type": "string",
"description": "Direct NCT ID lookup (NCT\\d{8})."
},
"phase": {
"type": "string",
"description": "PHASE1 | PHASE2 | PHASE3 | PHASE4 | NA | EARLY_PHASE1."
},
"query": {
"type": "string",
"description": "Free-text query (title/condition/intervention/sponsor)."
},
"status": {
"enum": [
"RECRUITING",
"ACTIVE_NOT_RECRUITING",
"COMPLETED",
"TERMINATED",
"WITHDRAWN",
"NOT_YET_RECRUITING",
"SUSPENDED"
],
"type": "string"
},
"country": {
"type": "string",
"description": "Country name (e.g., \"United States\")."
},
"sponsor": {
"type": "string",
"description": "Lead sponsor name filter."
},
"pageSize": {
"type": "integer",
"default": 10,
"maximum": 100,
"minimum": 1
},
"pageToken": {
"type": "string",
"description": "Opaque token from prior response (pagination)."
}
}
}
}
}
}
}
}
}Provenance
- Seen in the source catalog
- 2026-06-18 05:29Z
- Last indexed by Roundhouse
- 2026-07-17 19:20Z
- Last enriched (probe, favicon, geo)
- 2026-09-14 10:45Z
- x402 version
- 2
- Max timeout
- 60s
- Liveness probe
- HTTP 402
Hand this page to an agent
Copy the prompt and paste it into Claude, an MCP client or your own agent — it will vet this service and call it over the free read API. No key, no account.
GET api.roundhouseai.io/v0/endpoints
No per-endpoint history for this service yet, so this is payments indexed to its PROVIDER's wallet over 30 days. Verified volume counts only settlements with an on-chain EIP-3009 marker.
Show the promptHide the prompt
Using Roundhouse, look up the x402 service 2s and tell me whether it is worth paying: what a call costs, whether the endpoint answered when last probed, and what its payment record actually shows. curl -s 'https://api.roundhouseai.io/v0/endpoints?q=2s' curl -s 'https://api.roundhouseai.io/v0/merchants/<the payTo wallet returned above>' Then call it: read the price from the live 402 at https://2s.io/api/clinical/trial-search, never from a cached figure, and pay with an x402 client. The /v0 API needs an API key (`authorization: Bearer rh_live_…`) on everything except /v0/unified* and /v0/endpoints. Mint a personal key for $0.01 at GET https://api.roundhouseai.io/v0/test/x402, or use an organization key from https://roundhouseai.io/dashboard/team. If you do not have Roundhouse tools or skills installed, read https://roundhouseai.io/skill.md first — it is the whole procedure.