2s
The (most) everything API: 575+ pay-per-call endpoints for AI agents — ground-truth data, a full AI gateway, and agent infrastructure (storage, queues, watchers). USDC via x402, no signup, no API keys, and upto billing: pay actual usage, not the quote.
SearchLiveeip155:8453Exactvia cdp
Public-recordsIdentifiersAi-agentsUs-gov-datax402
Settlements · 30d
1,178↑ 64%
No per-endpoint history for this service yet, so this is payments indexed to its PROVIDER's wallet over 30 days.
$15.85
Verified settled volume
A floor: summed over 5,000 of 36,082 verified settlements.
$0.0011
Listed price
As published in the catalog. Always read the live 402 before paying.
2
Calls · 30d
Upstream's own call count for this endpoint, not ours.
2
Unique payers · 30d
Last called 2026-06-21 05:45Z
—
Upstream on-chain volume
Reported by the source catalog.
Paid to
0x2b6D4988Db4723E6908Db86Ab2b8dFBc51FC32C5The wallet the 402 directs payment to. Its whole payment record — every payer, every chain — is on the merchant page.
Asset 0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913
Provider
The payTo wallet does not resolve to a registered ERC-8004 agent. That is not a verdict on the service — most of the catalog is unregistered.
Live 402 challenge
Captured by the enrichment pass, not read just now. Prices can change — always read the 402 the endpoint answers with.
{
"error": "PAYMENT-SIGNATURE required",
"accepts": [
{
"asset": "0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913",
"extra": {
"name": "USD Coin",
"version": "2"
},
"payTo": "0x2b6D4988Db4723E6908Db86Ab2b8dFBc51FC32C5",
"amount": "2700",
"scheme": "exact",
"network": "eip155:8453",
"maxTimeoutSeconds": 60
},
{
"asset": "EPjFWdd5AufqSSqeM2qN1xzybapC8G4wEGGkZwyTDt1v",
"extra": {
"name": "USDC",
"version": "1",
"feePayer": "GVJJ7rdGiXr5xaYbRwRbjfaJL7fmwRygFi1H6aGqDveb"
},
"payTo": "TW6ntaGzvj63ZgPjszd4FCGmVTGfzv1MAYZbjYcyWhn",
"amount": "2700",
"scheme": "exact",
"network": "solana:5eykt4UsFv8P8NJdTREpY1vzqKqZKvdp",
"maxTimeoutSeconds": 60
}
],
"resource": {
"url": "https://2s.io/api/medical/genetics",
"tags": [
"public-records",
"identifiers",
"ai-agents",
"us-gov-data",
"x402",
"upto-billing",
"ai-gateway",
"agent-infrastructure"
],
"iconUrl": "https://2s.io/icon-512.png",
"mimeType": "application/json",
"description": "MedlinePlus Genetics (US National Library of Medicine) reference on a genetic condition or gene. Give a term (e.g. \"cystic fibrosis\", \"BRCA1\", \"sickle cell\") and get back the authoritative NLM record: the condition/gene name, a plain-language summary, the full set of sections (description, causes, frequency, inheritance, treatment), the inheritance pattern(s), related genes (with links), synonyms, and cross-references to other databases (OMIM, GTR, ICD-10-CM, …). Free, public-domain (NLM). Authoritative genetics reference an LLM cannot recite reliably — for clinical, patient-education, and research agents. Educational reference, not medical advice.",
"serviceName": "2s"
},
"extensions": {
"bazaar": {
"info": {
"input": {
"type": "http",
"method": "GET",
"queryParams": {
"term": "cystic fibrosis"
}
},
"output": {
"type": "json",
"schema": {
"type": "object",
"properties": {
"ok": {
"type": "boolean"
},
"items": {
"type": "array",
"items": {
"type": "object",
"properties": {
"url": {
"type": "string"
},
"name": {
"type": "string"
},
"type": {
"type": "string"
},
"query": {
"type": "object",
"properties": {
"slug": {
"type": "string"
},
"term": {
"type": "string"
},
"type": {
"type": "string"
}
}
},
"summary": {
"type": "string"
},
"sections": {
"type": "array",
"items": {
"type": "object",
"properties": {
"role": {
"type": "string"
},
"text": {
"type": "string"
}
}
}
},
"synonyms": {
"type": "array",
"items": {
"type": "string"
}
},
"relatedGenes": {
"type": "array",
"items": {
"type": "object",
"properties": {
"url": {
"type": "string"
},
"symbol": {
"type": "string"
}
}
}
},
"crossReferences": {
"type": "array",
"items": {
"type": "object",
"properties": {
"db": {
"type": "string"
},
"key": {
"type": "string"
}
}
}
},
"inheritancePatterns": {
"type": "array",
"items": {
"type": "string"
}
}
}
}
},
"total": {
"type": "integer"
},
"source": {
"type": "object",
"properties": {
"url": {
"type": "string"
},
"license": {
"type": "string"
},
"provider": {
"type": "string"
}
}
}
}
},
"example": {
"ok": true,
"items": [
{
"url": "https://medlineplus.gov/genetics/condition/cystic-fibrosis",
"name": "Cystic fibrosis",
"type": "condition",
"query": {
"slug": "cystic-fibrosis",
"term": "cystic fibrosis",
"type": "condition"
},
"summary": "Cystic fibrosis is an inherited disorder that causes severe damage to the lungs, digestive system…",
"sections": [
{
"role": "description",
"text": "Cystic fibrosis is an inherited disorder…"
}
],
"synonyms": [
"CF",
"Cystic fibrosis of pancreas"
],
"relatedGenes": [
{
"url": "https://medlineplus.gov/genetics/gene/cftr",
"symbol": "CFTR"
}
],
"crossReferences": [
{
"db": "ICD-10-CM",
"key": "E84"
},
{
"db": "GTR",
"key": "C0010674"
}
],
"inheritancePatterns": [
"Autosomal recessive"
]
}
],
"total": 1,
"source": {
"url": "https://medlineplus.gov/genetics/",
"license": "Public domain (US Government work). Live-wrapped.",
"provider": "U.S. National Library of Medicine — MedlinePlus Genetics"
}
}
}
},
"schema": {
"type": "object",
"$schema": "https://json-schema.org/draft/2020-12/schema",
"required": [
"input"
],
"properties": {
"input": {
"type": "object",
"required": [
"type",
"method",
"queryParams"
],
"properties": {
"type": {
"const": "http"
},
"method": {
"const": "GET"
},
"queryParams": {
"required": [
"term"
],
"properties": {
"term": {
"type": "string",
"description": "Condition or gene name (e.g. \"cystic fibrosis\", \"BRCA1\")."
}
}
}
}
},
"output": {
"type": "object",
"properties": {
"ok": {
"type": "boolean"
},
"items": {
"type": "array",
"items": {
"type": "object",
"properties": {
"url": {
"type": "string"
},
"name": {
"type": "string"
},
"type": {
"type": "string"
},
"query": {
"type": "object",
"properties": {
"slug": {
"type": "string"
},
"term": {
"type": "string"
},
"type": {
"type": "string"
}
}
},
"summary": {
"type": "string"
},
"sections": {
"type": "array",
"items": {
"type": "object",
"properties": {
"role": {
"type": "string"
},
"text": {
"type": "string"
}
}
}
},
"synonyms": {
"type": "array",
"items": {
"type": "string"
}
},
"relatedGenes": {
"type": "array",
"items": {
"type": "object",
"properties": {
"url": {
"type": "string"
},
"symbol": {
"type": "string"
}
}
}
},
"crossReferences": {
"type": "array",
"items": {
"type": "object",
"properties": {
"db": {
"type": "string"
},
"key": {
"type": "string"
}
}
}
},
"inheritancePatterns": {
"type": "array",
"items": {
"type": "string"
}
}
}
}
},
"total": {
"type": "integer"
},
"source": {
"type": "object",
"properties": {
"url": {
"type": "string"
},
"license": {
"type": "string"
},
"provider": {
"type": "string"
}
}
}
}
}
}
}
}
},
"x402Version": 2
}Accepts
The payment requirements as published to the catalog. Read the live 402 before paying — a price here is a claim, not a quote.
0.00108USDC≈ $0.00108 USD
on Base · exact scheme
Pay 0.00108 USDC on Base to 0x2b6D…C32C5. The signed payment is good for 1 minute.
- Paid to
- 0x2b6D…C32C5
- USD Coin contract
- 0x8335…02913
- Payment window
- 1 minute
- As published
- 1080 smallest units
1080units
on solana:5eykt4UsFv8P8NJdTREpY1vzqKqZKvdp · exact scheme
That figure is in the token’s smallest units. Roundhouse does not hold this contract’s decimals, so it is shown as published rather than converted.
- Paid to
- TW6nta…cyWhn
- Token contract
- EPjFWd…TDt1v
- Payment window
- 1 minute
The catalog’s raw entry
[
{
"asset": "0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913",
"extra": {
"name": "USD Coin",
"version": "2"
},
"payTo": "0x2b6D4988Db4723E6908Db86Ab2b8dFBc51FC32C5",
"amount": "1080",
"scheme": "exact",
"network": "eip155:8453",
"maxTimeoutSeconds": 60
},
{
"asset": "EPjFWdd5AufqSSqeM2qN1xzybapC8G4wEGGkZwyTDt1v",
"extra": {
"name": "USDC",
"version": "1",
"feePayer": "D6ZhtNQ5nT9ZnTHUbqXZsTx5MH2rPFiBBggX4hY1WePM"
},
"payTo": "TW6ntaGzvj63ZgPjszd4FCGmVTGfzv1MAYZbjYcyWhn",
"amount": "1080",
"scheme": "exact",
"network": "solana:5eykt4UsFv8P8NJdTREpY1vzqKqZKvdp",
"maxTimeoutSeconds": 60
}
]Extensions
{
"bazaar": {
"info": {
"input": {
"type": "http",
"method": "GET",
"queryParams": {
"term": "cystic fibrosis"
}
},
"output": {
"type": "json",
"schema": {
"type": "object",
"properties": {
"ok": {
"type": "boolean"
},
"items": {
"type": "array",
"items": {
"type": "object",
"properties": {
"url": {
"type": "string"
},
"name": {
"type": "string"
},
"type": {
"type": "string"
},
"query": {
"type": "object",
"properties": {
"slug": {
"type": "string"
},
"term": {
"type": "string"
},
"type": {
"type": "string"
}
}
},
"summary": {
"type": "string"
},
"sections": {
"type": "array",
"items": {
"type": "object",
"properties": {
"role": {
"type": "string"
},
"text": {
"type": "string"
}
}
}
},
"synonyms": {
"type": "array",
"items": {
"type": "string"
}
},
"relatedGenes": {
"type": "array",
"items": {
"type": "object",
"properties": {
"url": {
"type": "string"
},
"symbol": {
"type": "string"
}
}
}
},
"crossReferences": {
"type": "array",
"items": {
"type": "object",
"properties": {
"db": {
"type": "string"
},
"key": {
"type": "string"
}
}
}
},
"inheritancePatterns": {
"type": "array",
"items": {
"type": "string"
}
}
}
}
},
"total": {
"type": "integer"
},
"source": {
"type": "object",
"properties": {
"url": {
"type": "string"
},
"license": {
"type": "string"
},
"provider": {
"type": "string"
}
}
}
}
},
"example": {
"ok": true,
"items": [
{
"url": "https://medlineplus.gov/genetics/condition/cystic-fibrosis",
"name": "Cystic fibrosis",
"type": "condition",
"query": {
"slug": "cystic-fibrosis",
"term": "cystic fibrosis",
"type": "condition"
},
"summary": "Cystic fibrosis is an inherited disorder that causes severe damage to the lungs, digestive system…",
"sections": [
{
"role": "description",
"text": "Cystic fibrosis is an inherited disorder…"
}
],
"synonyms": [
"CF",
"Cystic fibrosis of pancreas"
],
"relatedGenes": [
{
"url": "https://medlineplus.gov/genetics/gene/cftr",
"symbol": "CFTR"
}
],
"crossReferences": [
{
"db": "ICD-10-CM",
"key": "E84"
},
{
"db": "GTR",
"key": "C0010674"
}
],
"inheritancePatterns": [
"Autosomal recessive"
]
}
],
"total": 1,
"source": {
"url": "https://medlineplus.gov/genetics/",
"license": "Public domain (US Government work). Live-wrapped.",
"provider": "U.S. National Library of Medicine — MedlinePlus Genetics"
}
}
}
},
"schema": {
"type": "object",
"$schema": "https://json-schema.org/draft/2020-12/schema",
"required": [
"input"
],
"properties": {
"input": {
"type": "object",
"required": [
"type",
"method",
"queryParams"
],
"properties": {
"type": {
"const": "http"
},
"method": {
"const": "GET"
},
"queryParams": {
"required": [
"term"
],
"properties": {
"term": {
"type": "string",
"description": "Condition or gene name (e.g. \"cystic fibrosis\", \"BRCA1\")."
}
}
}
}
},
"output": {
"type": "object",
"properties": {
"ok": {
"type": "boolean"
},
"items": {
"type": "array",
"items": {
"type": "object",
"properties": {
"url": {
"type": "string"
},
"name": {
"type": "string"
},
"type": {
"type": "string"
},
"query": {
"type": "object",
"properties": {
"slug": {
"type": "string"
},
"term": {
"type": "string"
},
"type": {
"type": "string"
}
}
},
"summary": {
"type": "string"
},
"sections": {
"type": "array",
"items": {
"type": "object",
"properties": {
"role": {
"type": "string"
},
"text": {
"type": "string"
}
}
}
},
"synonyms": {
"type": "array",
"items": {
"type": "string"
}
},
"relatedGenes": {
"type": "array",
"items": {
"type": "object",
"properties": {
"url": {
"type": "string"
},
"symbol": {
"type": "string"
}
}
}
},
"crossReferences": {
"type": "array",
"items": {
"type": "object",
"properties": {
"db": {
"type": "string"
},
"key": {
"type": "string"
}
}
}
},
"inheritancePatterns": {
"type": "array",
"items": {
"type": "string"
}
}
}
}
},
"total": {
"type": "integer"
},
"source": {
"type": "object",
"properties": {
"url": {
"type": "string"
},
"license": {
"type": "string"
},
"provider": {
"type": "string"
}
}
}
}
}
}
}
}
}Provenance
- Seen in the source catalog
- 2026-06-21 05:45Z
- Last indexed by Roundhouse
- 2026-07-16 20:50Z
- Last enriched (probe, favicon, geo)
- 2026-09-23 09:45Z
- x402 version
- 2
- Max timeout
- 60s
- Liveness probe
- HTTP 402
Hand this page to an agent
Copy the prompt and paste it into Claude, an MCP client or your own agent — it will vet this service and call it over the free read API. No key, no account.
GET api.roundhouseai.io/v0/endpoints
No per-endpoint history for this service yet, so this is payments indexed to its PROVIDER's wallet over 30 days. Verified volume counts only settlements with an on-chain EIP-3009 marker.
Show the promptHide the prompt
Using Roundhouse, look up the x402 service 2s and tell me whether it is worth paying: what a call costs, whether the endpoint answered when last probed, and what its payment record actually shows. curl -s 'https://api.roundhouseai.io/v0/endpoints?q=2s' curl -s 'https://api.roundhouseai.io/v0/merchants/<the payTo wallet returned above>' Then call it: read the price from the live 402 at https://2s.io/api/medical/genetics, never from a cached figure, and pay with an x402 client. The /v0 API needs an API key (`authorization: Bearer rh_live_…`) on everything except /v0/unified* and /v0/endpoints. Mint a personal key for $0.01 at GET https://api.roundhouseai.io/v0/test/x402, or use an organization key from https://roundhouseai.io/dashboard/team. If you do not have Roundhouse tools or skills installed, read https://roundhouseai.io/skill.md first — it is the whole procedure.