Research dose-response fit

Fit normalized assay responses using a fixed-bottom/top logit-linear Hill model. Return half-response, slope and residuals; no dosing or nonlinear-fit guarantee. New modular adapter: retained result recovery for 24 hours, minimal receipt metadata for 90 days. Existing live route unchanged.

SearchLiveeip155:8453Exactvia cdp
ComputeBiologyResearch-dose-response-fitBounded-computationEvidence
Calls · 30d
1→ 0%
This endpoint's own trailing-30-day call count, as published by the upstream catalog and snapshotted daily. 4 snapshots so far.
$80.58
Verified settled volume
1,351 settlements proven x402 by their on-chain EIP-3009 marker.
$0.105
Listed price
As published in the catalog. Always read the live 402 before paying.
1
Calls · 30d
Upstream's own call count for this endpoint, not ours.
1
Unique payers · 30d
Last called 2026-10-15 14:39Z
–
Upstream on-chain volume
Reported by the source catalog.
Paid to
0xec84c1cd6602bbe387bc8e6f0d3c062f2762de28

The wallet the 402 directs payment to. Its full payment record is on the merchant page.

Asset 0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913

Provider

The payTo wallet does not resolve to a registered ERC-8004 agent. That is not a verdict on the service; most of the catalog is unregistered.

Recent payments · which agents last used it

Every indexed settlement paid to this service’s wallet, newest first. The index does not record which endpoint a payment was for, so if this wallet serves more than one endpoint, the rows include payments for the others. Paged up to the newest 5,000; the full history is on the merchant page.

Payer PayeeChainAmountx402RouteAgeTxn hash
0x7b7f…46f20xec84…de28BaseBase$0.18100%coinbase11h ago0xfb5454…ad9dda
0x7b7f…46f20xec84…de28BaseBase$0.14100%coinbase22h ago0x9ad9c1…60be69
0x7b7f…46f20xec84…de28BaseBase$0.21100%coinbase23h ago0x2a1d51…1dfdf6
0x7b7f…46f20xec84…de28BaseBase$0.17100%coinbase23h ago0x3c51db…a3e7ed
0x7b7f…46f20xec84…de28BaseBase$0.21100%coinbase23h ago0x5e4443…cd6b0d
0x7b7f…46f20xec84…de28BaseBase$0.18100%coinbase23h ago0x4a3cde…ede679
0x7b7f…46f20xec84…de28BaseBase$0.19100%coinbase1d ago0x9dee69…de4bde
0x7b7f…46f20xec84…de28BaseBase$0.21100%coinbase1d ago0x7f248b…00697c
0x7b7f…46f20xec84…de28BaseBase$0.18100%coinbase1d ago0xf59ec0…91a5cc
0x7b7f…46f20xec84…de28BaseBase$0.19100%coinbase1d ago0x0af2ec…f6facc
0x7b7f…46f20xec84…de28BaseBase$0.22100%coinbase1d ago0x9fe6c8…255a0d
0x7b7f…46f20xec84…de28BaseBase$0.23100%coinbase1d ago0x2b8bbe…f533fb
0x7b7f…46f20xec84…de28BaseBase$0.17100%coinbase1d ago0xa37008…689628
0x7b7f…46f20xec84…de28BaseBase$0.16100%coinbase1d ago0xb8bb5a…73718e
0x7b7f…46f20xec84…de28BaseBase$0.18100%coinbase1d ago0xc8c4d9…7a8203
0x7b7f…46f20xec84…de28BaseBase$0.16100%coinbase1d ago0x5cfffa…00de60
0x7b7f…46f20xec84…de28BaseBase$0.13100%coinbase1d ago0xee3704…69f1de
0x7b7f…46f20xec84…de28BaseBase$0.21100%coinbase1d ago0x3d4c6d…6482ff
0x7b7f…46f20xec84…de28BaseBase$0.19100%coinbase1d ago0xc0bdae…473c9c
0x7b7f…46f20xec84…de28BaseBase$0.15100%coinbase1d ago0x590673…35b839
0x7b7f…46f20xec84…de28BaseBase$0.18100%coinbase1d ago0x0803f0…088aff
0x7b7f…46f20xec84…de28BaseBase$0.12100%coinbase1d ago0xf0b3db…b7415e
0x7b7f…46f20xec84…de28BaseBase$0.21100%coinbase1d ago0x540f0f…6ef8c7
0x7b7f…46f20xec84…de28BaseBase$0.15100%coinbase1d ago0xde7cb2…eb2fc1
0x7b7f…46f20xec84…de28BaseBase$0.22100%coinbase1d ago0x9639a1…e37ec8

Accepts

The payment requirements as published to the catalog. Read the live 402 before paying: a price here is a claim, not a quote.

0.105001USDC≈ $0.105001 USD
on Base · exact scheme

Pay 0.105001 USDC on Base to 0xec84…2de28. The signed payment is good for 1 minute.

USD Coin contract
0x8335…02913
Payment window
1 minute
As published
105001 smallest units
The catalog’s raw entry
[
  {
    "asset": "0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913",
    "extra": {
      "name": "USD Coin",
      "version": "2"
    },
    "payTo": "0xec84c1cd6602bbe387bc8e6f0d3c062f2762de28",
    "amount": "105001",
    "scheme": "exact",
    "network": "eip155:8453",
    "maxTimeoutSeconds": 60
  }
]

Extensions

{
  "bazaar": {
    "info": {
      "input": {
        "body": {
          "dose": [
            1,
            2,
            4,
            8
          ],
          "dataClass": "synthetic",
          "normalizedResponse": [
            0.2,
            0.3333333333333333,
            0.5,
            0.6666666666666666
          ]
        },
        "type": "http",
        "method": "POST",
        "bodyType": "json"
      },
      "output": {
        "type": "json",
        "example": {
          "data": {
            "result": {
              "findings": {
                "method": "fixed bottom=0 top=1 logit-linear Hill fit; endpoints excluded, …",
                "hillSlope": 1,
                "residuals": [
                  0
                ],
                "transformedFit": {
                  "slope": 1,
                  "rSquared": 1,
                  "intercept": -1.38629436112,
                  "residuals": [
                    0
                  ],
                  "degreesOfFreedom": 2,
                  "slopeStandardError": 5.0650620345e-17,
                  "residualStandardError": 7.85046229342e-17
                },
                "halfResponseDose": 4,
                "clinicalInterpretation": false
              },
              "limitations": [
                "Public or synthetic research inputs only; no patient, personal g…"
              ],
              "methodVersion": "maha-science50/1.0.0",
              "numericPrecision": "IEEE754-double; finite outputs rounded to 12 significant digits"
            },
            "version": "maha-legacy-adapter/1",
            "inputHash": "sha256:fe93359c4121213e671050f69c3060886be624e2ed9f58e3028291322…",
            "productId": "biology-research-dose-response-fit",
            "resultHash": "sha256:4ee757ea4439ed00e411afafabbf8b9c9b86d5e7eba57cac813b0a580…",
            "limitations": [
              "Public or synthetic inputs only. Caller labels are declarations,…"
            ],
            "chargedAmount": "105001",
            "sourceContractAmount": "105000"
          },
          "proof": {
            "settlement_id": "0x00000000000000000000000000000000000000000000000000000000000000…"
          },
          "success": true
        }
      }
    },
    "schema": {
      "type": "object",
      "$schema": "https://json-schema.org/draft/2020-12/schema",
      "required": [
        "input"
      ],
      "properties": {
        "input": {
          "type": "object",
          "required": [
            "type",
            "method",
            "bodyType",
            "body"
          ],
          "properties": {
            "body": {
              "type": "object",
              "required": [
                "dataClass",
                "dose",
                "normalizedResponse"
              ],
              "properties": {
                "dose": {
                  "type": "array",
                  "maxItems": 128,
                  "minItems": 1
                },
                "dataClass": {
                  "enum": [
                    "public",
                    "synthetic"
                  ],
                  "type": "string"
                },
                "normalizedResponse": {
                  "type": "array",
                  "maxItems": 128,
                  "minItems": 1
                }
              },
              "additionalProperties": false
            },
            "type": {
              "type": "string",
              "const": "http"
            },
            "method": {
              "enum": [
                "POST"
              ],
              "type": "string"
            },
            "bodyType": {
              "enum": [
                "json",
                "form-data",
                "text"
              ],
              "type": "string"
            }
          },
          "additionalProperties": false
        },
        "output": {
          "type": "object",
          "required": [
            "type"
          ],
          "properties": {
            "type": {
              "type": "string"
            },
            "example": {
              "type": "object",
              "required": [
                "success",
                "data",
                "proof"
              ],
              "properties": {
                "data": {
                  "type": "object"
                },
                "proof": {
                  "type": "object"
                },
                "success": {
                  "const": true
                }
              },
              "additionalProperties": false
            }
          }
        }
      }
    }
  },
  "maha-modular-contract": {
    "info": {
      "id": "biology-research-dose-response-fit",
      "contractHash": "sha256:69ce1020e7e09898b52e8ca8d0025793d02319ef8e0a43518f87a7d523564d34",
      "declarationUrl": "https://www.mahastrategies.com/api/v1/discovery/describe?id=biology-research-dose-response-fit",
      "requiresBuyerRecoveryAdapter": true
    },
    "schema": {
      "type": "object"
    }
  },
  "maha-input-bound-recovery": {
    "info": {
      "binding": {
        "nonce": "0x + lowercase HEX(SHA256(RFC8785({version,productId,inputHash,recoverySecret})))",
        "version": "maha-api-v1/1",
        "inputHash": "sha256: + lowercase HEX(SHA256(RFC8785(strictly parsed input)))",
        "productId": "biology-research-dose-response-fit",
        "recoverySecret": "32 cryptographically random bytes encoded as 64 lowercase hexadecimal characters; keep private",
        "automaticRepayment": false,
        "paymentSignatureHeader": "base64 x402-v2 PaymentPayload with EIP-3009 TransferWithAuthorization"
      },
      "version": "1",
      "withdrawal": "stops-new-purchases; retained-paid-result-remains-recoverable",
      "secretHeader": "X-Maha-Recovery-Secret",
      "inputHashHeader": "X-Maha-Input-Hash",
      "retentionSeconds": 86400,
      "automaticRepayment": false,
      "complimentaryCorrection": false,
      "receiptRetentionSeconds": 7776000
    },
    "schema": {
      "type": "object"
    }
  }
}

Provenance

Seen in the source catalog
2026-10-15 14:39Z
Last indexed by Roundhouse
2026-10-19 01:30Z
Last enriched (probe, favicon, geo)
2026-10-16 10:16Z
x402 version
2
Max timeout
60s
Liveness probe
HTTP 404
Report

Hand this page to an agent

Copy the prompt and paste it into Claude, an MCP client or your own agent: it will vet this service and call it over the free read API. No key, no account.

GET api.roundhouseai.io/v0/endpoints

This endpoint's own trailing-30-day call count, as published by the upstream catalog and snapshotted daily. 4 snapshots so far. Verified volume counts only settlements with an on-chain EIP-3009 marker.

Open skill.md
Show the prompt
Using Roundhouse, look up the x402 service Research dose-response fit and tell me whether it is
worth paying: what a call costs, whether the endpoint answered when last probed, and what
its payment record actually shows.

curl -s 'https://api.roundhouseai.io/v0/endpoints?q=Research%20dose-response%20fit'
curl -s 'https://api.roundhouseai.io/v0/merchants/<the payTo wallet returned above>'

Then call it: read the price from the live 402 at https://www.mahastrategies.com/api/v1/compute/biology/research-dose-response-fit, never from
a cached figure, and pay with an x402 client.

The /v0 API needs an API key (`authorization: Bearer rh_live_…`) on everything except
/v0/unified* and /v0/endpoints. Either pay over x402 (mint a personal key for $0.01 at
GET https://api.roundhouseai.io/v0/test/x402), or ask me for an organization key, which I create at
https://roundhouseai.io/dashboard/connections. If you have neither, ask before going further.

If you do not have Roundhouse tools or skills installed, read
https://roundhouseai.io/skill.md first — it is the whole procedure.