api.biotechcatalystsentinel.com

A machine-first oracle for upcoming FDA PDUFA decision dates, extracted from primary SEC filings and accuracy-backtested against actual FDA decisions. Two paid endpoints over x402 (Base or Solana USDC) — upcoming dates and the catalyst change history; plus a free, auditable accuracy track record.

TradingLiveeip155:8453Exactvia cdp
Calls · 30d
24↑ 9.2%
This endpoint's own trailing-30-day call count, as published by the upstream catalog and snapshotted daily. 32 snapshots so far.
$1.79
Verified settled volume
61 settlements proven x402 by their on-chain EIP-3009 marker.
$0.020
Listed price
As published in the catalog. Always read the live 402 before paying.
18
Calls · 30d
Upstream's own call count for this endpoint, not ours.
9
Unique payers · 30d
Last called 2026-09-24 02:14Z
Upstream on-chain volume
Reported by the source catalog.
Paid to
0xcD8975137D48ED9bfD1C299a62c01420B860070d

The wallet the 402 directs payment to. Its whole payment record — every payer, every chain — is on the merchant page.

Asset 0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913

Provider

The payTo wallet does not resolve to a registered ERC-8004 agent. That is not a verdict on the service — most of the catalog is unregistered.

Live 402 challenge

Captured by the enrichment pass, not read just now. Prices can change — always read the 402 the endpoint answers with.

{
  "error": "Payment required",
  "accepts": [
    {
      "asset": "0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913",
      "extra": {
        "name": "USD Coin",
        "version": "2"
      },
      "payTo": "0xcD8975137D48ED9bfD1C299a62c01420B860070d",
      "amount": "20000",
      "scheme": "exact",
      "network": "eip155:8453",
      "maxTimeoutSeconds": 300
    },
    {
      "asset": "EPjFWdd5AufqSSqeM2qN1xzybapC8G4wEGGkZwyTDt1v",
      "extra": {
        "feePayer": "BENrLoUbndxoNMUS5JXApGMtNykLjFXXixMtpDwDR9SP"
      },
      "payTo": "3gM4YDDPAi7w1di7rHAAaHc5T1tR7NRXzLWzPPN4ZRaM",
      "amount": "20000",
      "scheme": "exact",
      "network": "solana:5eykt4UsFv8P8NJdTREpY1vzqKqZKvdp",
      "maxTimeoutSeconds": 300
    }
  ],
  "resource": {
    "url": "https://api.biotechcatalystsentinel.com/v1/catalysts/upcoming",
    "mimeType": "application/json",
    "description": "Upcoming FDA drug-approval (PDUFA) decision dates for US-listed biotechs — a forward catalyst calendar from primary SEC 8-K/6-K filings, every date grounded in a verbatim filing quote, cited to its EDGAR accession and later scored against the actual FDA decision. Use when you need the next 1-365 days of binary FDA events, whole feed or one ticker. Verify accuracy AND coverage free at GET /v1/accuracy before you pay. Flat price per request."
  },
  "extensions": {
    "bazaar": {
      "info": {
        "input": {
          "type": "http",
          "method": "GET",
          "queryParams": {
            "limit": 200,
            "within_days": 365
          }
        },
        "output": {
          "type": "json",
          "example": {
            "data": [
              {
                "cik": "0009999001",
                "stage": "set",
                "ticker": "XSMPL",
                "company": "Sample Therapeutics, Inc.",
                "tickers": [
                  "XSMPL",
                  "XPRTN"
                ],
                "age_days": 12,
                "authority": "llm_high",
                "drug_name": "SAMPLIMAB",
                "confidence": "high",
                "indication": "sample indication (moderate-to-severe examplitis)",
                "pdufa_date": "2026-11-15",
                "source_url": "https://www.sec.gov/Archives/edgar/data/9999001/000999900126000001/0009999001-26-000001-index.htm",
                "catalyst_id": 990001,
                "last_updated": "2026-07-20T14:02:11.000000+00:00",
                "source_quote": "The FDA has set a Prescription Drug User Fee Act (PDUFA) target action date of November 15, 2026 for SAMPLIMAB. [FICTIONAL SAMPLE — not a real filing sentence]",
                "date_confidence": "confirmed",
                "source_accession": "0009999001-26-000001",
                "application_number": "BLA999901"
              }
            ],
            "meta": {
              "limit": 200,
              "total": 1,
              "has_more": null,
              "next_since": null
            }
          }
        }
      },
      "schema": {
        "type": "object",
        "$schema": "https://json-schema.org/draft/2020-12/schema",
        "required": [
          "input"
        ],
        "properties": {
          "input": {
            "type": "object",
            "required": [
              "type",
              "method"
            ],
            "properties": {
              "type": {
                "type": "string",
                "const": "http"
              },
              "method": {
                "enum": [
                  "GET",
                  "HEAD",
                  "DELETE"
                ],
                "type": "string"
              },
              "queryParams": {
                "type": "object",
                "required": [],
                "properties": {
                  "limit": {
                    "type": "integer",
                    "default": 200,
                    "maximum": 500,
                    "minimum": 1,
                    "description": "Maximum number of catalysts to return (1-500; default 200)."
                  },
                  "ticker": {
                    "type": "string",
                    "pattern": "^\\S+$",
                    "maxLength": 12,
                    "minLength": 1,
                    "description": "Optional server-side filter: only records filed by this ticker's issuer or exposing it as a co-filer in tickers[] (case-insensitive; the same membership the free /v1/coverage counts). Unknown ticker returns an empty 200. Omit for the whole feed. Does not change the price."
                  },
                  "within_days": {
                    "type": "integer",
                    "default": 365,
                    "maximum": 365,
                    "minimum": 1,
                    "description": "Only return catalysts whose PDUFA date falls within this many days from today (1-365; default 365)."
                  }
                }
              }
            },
            "additionalProperties": false
          },
          "output": {
            "type": "object",
            "required": [
              "type"
            ],
            "properties": {
              "type": {
                "type": "string"
              },
              "example": {
                "type": "object",
                "properties": {
                  "data": {
                    "type": "array",
                    "items": {
                      "type": "object",
                      "required": [
                        "catalyst_id",
                        "stage"
                      ],
                      "properties": {
                        "cik": {
                          "type": [
                            "string",
                            "null"
                          ]
                        },
                        "stage": {
                          "enum": [
                            "set",
                            "extended",
                            "resolved",
                            "crl"
                          ],
                          "type": "string"
                        },
                        "ticker": {
                          "type": [
                            "string",
                            "null"
                          ]
                        },
                        "company": {
                          "type": [
                            "string",
                            "null"
                          ]
                        },
                        "tickers": {
                          "type": "array",
                          "items": {
                            "type": "string"
                          }
                        },
                        "age_days": {
                          "type": [
                            "integer",
                            "null"
                          ]
                        },
                        "authority": {
                          "enum": [
                            "human_lock",
                            "llm_high",
                            "regex",
                            "llm_medium",
                            "llm_low",
                            null
                          ],
                          "type": [
                            "string",
                            "null"
                          ]
                        },
                        "drug_name": {
                          "type": [
                            "string",
                            "null"
                          ]
                        },
                        "confidence": {
                          "enum": [
                            "high",
                            "medium",
                            "low",
                            null
                          ],
                          "type": [
                            "string",
                            "null"
                          ]
                        },
                        "indication": {
                          "type": [
                            "string",
                            "null"
                          ]
                        },
                        "pdufa_date": {
                          "type": [
                            "string",
                            "null"
                          ]
                        },
                        "source_url": {
                          "type": [
                            "string",
                            "null"
                          ]
                        },
                        "catalyst_id": {
                          "type": "integer"
                        },
                        "last_updated": {
                          "type": [
                            "string",
                            "null"
                          ]
                        },
                        "source_quote": {
                          "type": [
                            "string",
                            "null"
                          ]
                        },
                        "date_confidence": {
                          "enum": [
                            "confirmed",
                            "reported",
                            "estimated",
                            null
                          ],
                          "type": [
                            "string",
                            "null"
                          ]
                        },
                        "source_accession": {
                          "type": [
                            "string",
                            "null"
                          ]
                        },
                        "application_number": {
                          "type": [
                            "string",
                            "null"
                          ]
                        }
                      }
                    },
                    "description": "One row per upcoming FDA decision. One decision is ONE row even when several public companies file on it (sponsor, originator, royalty holder) — filter on the `tickers` array, not the single `ticker`, or you will miss catalysts a partner is exposed to."
                  },
                  "meta": {
                    "type": "object",
                    "description": "Result metadata, e.g. total count."
                  }
                }
              }
            }
          }
        }
      }
    }
  },
  "x402Version": 2
}

Accepts

The payment requirements as published to the catalog. Read the live 402 before paying — a price here is a claim, not a quote.

0.02USDC≈ $0.02 USD
on Base · exact scheme

Pay 0.02 USDC on Base to 0xcD89…0070d. The signed payment is good for 5 minutes.

USD Coin contract
0x8335…02913
Payment window
5 minutes
As published
20000 smallest units
20000units
on solana:5eykt4UsFv8P8NJdTREpY1vzqKqZKvdp · exact scheme

That figure is in the token’s smallest units. Roundhouse does not hold this contract’s decimals, so it is shown as published rather than converted.

Token contract
EPjFWd…TDt1v
Payment window
5 minutes
The catalog’s raw entry
[
  {
    "asset": "0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913",
    "extra": {
      "name": "USD Coin",
      "version": "2"
    },
    "payTo": "0xcD8975137D48ED9bfD1C299a62c01420B860070d",
    "amount": "20000",
    "scheme": "exact",
    "network": "eip155:8453",
    "maxTimeoutSeconds": 300
  },
  {
    "asset": "EPjFWdd5AufqSSqeM2qN1xzybapC8G4wEGGkZwyTDt1v",
    "extra": {
      "feePayer": "Hc3sdEAsCGQcpgfivywog9uwtk8gUBUZgsxdME1EJy88"
    },
    "payTo": "3gM4YDDPAi7w1di7rHAAaHc5T1tR7NRXzLWzPPN4ZRaM",
    "amount": "20000",
    "scheme": "exact",
    "network": "solana:5eykt4UsFv8P8NJdTREpY1vzqKqZKvdp",
    "maxTimeoutSeconds": 300
  }
]

Extensions

{
  "bazaar": {
    "info": {
      "input": {
        "type": "http",
        "method": "GET",
        "queryParams": {
          "limit": 200,
          "within_days": 365
        }
      },
      "output": {
        "type": "json",
        "example": {
          "data": [
            {
              "cik": "0009999001",
              "stage": "set",
              "ticker": "XSMPL",
              "company": "Sample Therapeutics, Inc.",
              "tickers": [
                "XSMPL",
                "XPRTN"
              ],
              "age_days": 12,
              "authority": "llm_high",
              "drug_name": "SAMPLIMAB",
              "confidence": "high",
              "indication": "sample indication (moderate-to-severe examplitis)",
              "pdufa_date": "2026-11-15",
              "source_url": "https://www.sec.gov/Archives/edgar/data/9999001/000999900126000001/0009999001-26-000001-index.htm",
              "catalyst_id": 990001,
              "last_updated": "2026-07-20T14:02:11.000000+00:00",
              "source_quote": "The FDA has set a Prescription Drug User Fee Act (PDUFA) target action date of November 15, 2026 for SAMPLIMAB. [FICTIONAL SAMPLE — not a real filing sentence]",
              "date_confidence": "confirmed",
              "source_accession": "0009999001-26-000001",
              "application_number": "BLA999901"
            }
          ],
          "meta": {
            "limit": 200,
            "total": 1,
            "has_more": null,
            "next_since": null
          }
        }
      }
    },
    "schema": {
      "type": "object",
      "$schema": "https://json-schema.org/draft/2020-12/schema",
      "required": [
        "input"
      ],
      "properties": {
        "input": {
          "type": "object",
          "required": [
            "type",
            "method"
          ],
          "properties": {
            "type": {
              "type": "string",
              "const": "http"
            },
            "method": {
              "enum": [
                "GET",
                "HEAD",
                "DELETE"
              ],
              "type": "string"
            },
            "queryParams": {
              "type": "object",
              "required": [],
              "properties": {
                "limit": {
                  "type": "integer",
                  "default": 200,
                  "maximum": 500,
                  "minimum": 1,
                  "description": "Maximum number of catalysts to return (1-500; default 200)."
                },
                "ticker": {
                  "type": "string",
                  "pattern": "^\\S+$",
                  "maxLength": 12,
                  "minLength": 1,
                  "description": "Optional server-side filter: only records filed by this ticker's issuer or exposing it as a co-filer in tickers[] (case-insensitive; the same membership the free /v1/coverage counts). Unknown ticker returns an empty 200. Omit for the whole feed. Does not change the price."
                },
                "within_days": {
                  "type": "integer",
                  "default": 365,
                  "maximum": 365,
                  "minimum": 1,
                  "description": "Only return catalysts whose PDUFA date falls within this many days from today (1-365; default 365)."
                }
              }
            }
          },
          "additionalProperties": false
        },
        "output": {
          "type": "object",
          "required": [
            "type"
          ],
          "properties": {
            "type": {
              "type": "string"
            },
            "example": {
              "type": "object",
              "properties": {
                "data": {
                  "type": "array",
                  "items": {
                    "type": "object",
                    "required": [
                      "catalyst_id",
                      "stage"
                    ],
                    "properties": {
                      "cik": {
                        "type": [
                          "string",
                          "null"
                        ]
                      },
                      "stage": {
                        "enum": [
                          "set",
                          "extended",
                          "resolved",
                          "crl"
                        ],
                        "type": "string"
                      },
                      "ticker": {
                        "type": [
                          "string",
                          "null"
                        ]
                      },
                      "company": {
                        "type": [
                          "string",
                          "null"
                        ]
                      },
                      "tickers": {
                        "type": "array",
                        "items": {
                          "type": "string"
                        }
                      },
                      "age_days": {
                        "type": [
                          "integer",
                          "null"
                        ]
                      },
                      "authority": {
                        "enum": [
                          "human_lock",
                          "llm_high",
                          "regex",
                          "llm_medium",
                          "llm_low",
                          null
                        ],
                        "type": [
                          "string",
                          "null"
                        ]
                      },
                      "drug_name": {
                        "type": [
                          "string",
                          "null"
                        ]
                      },
                      "confidence": {
                        "enum": [
                          "high",
                          "medium",
                          "low",
                          null
                        ],
                        "type": [
                          "string",
                          "null"
                        ]
                      },
                      "indication": {
                        "type": [
                          "string",
                          "null"
                        ]
                      },
                      "pdufa_date": {
                        "type": [
                          "string",
                          "null"
                        ]
                      },
                      "source_url": {
                        "type": [
                          "string",
                          "null"
                        ]
                      },
                      "catalyst_id": {
                        "type": "integer"
                      },
                      "last_updated": {
                        "type": [
                          "string",
                          "null"
                        ]
                      },
                      "source_quote": {
                        "type": [
                          "string",
                          "null"
                        ]
                      },
                      "date_confidence": {
                        "enum": [
                          "confirmed",
                          "reported",
                          "estimated",
                          null
                        ],
                        "type": [
                          "string",
                          "null"
                        ]
                      },
                      "source_accession": {
                        "type": [
                          "string",
                          "null"
                        ]
                      },
                      "application_number": {
                        "type": [
                          "string",
                          "null"
                        ]
                      }
                    }
                  },
                  "description": "One row per upcoming FDA decision. One decision is ONE row even when several public companies file on it (sponsor, originator, royalty holder) — filter on the `tickers` array, not the single `ticker`, or you will miss catalysts a partner is exposed to."
                },
                "meta": {
                  "type": "object",
                  "description": "Result metadata, e.g. total count."
                }
              }
            }
          }
        }
      }
    }
  }
}

Provenance

Seen in the source catalog
2026-09-24 02:14Z
Last indexed by Roundhouse
2026-09-24 08:40Z
Last enriched (probe, favicon, geo)
2026-09-12 22:15Z
x402 version
2
Max timeout
300s
Liveness probe
HTTP 402
Report

Hand this page to an agent

Copy the prompt and paste it into Claude, an MCP client or your own agent — it will vet this service and call it over the free read API. No key, no account.

GET api.roundhouseai.io/v0/endpoints

This endpoint's own trailing-30-day call count, as published by the upstream catalog and snapshotted daily. 32 snapshots so far. Verified volume counts only settlements with an on-chain EIP-3009 marker.

Open skill.md
Show the prompt
Using Roundhouse, look up the x402 service api.biotechcatalystsentinel.com and tell me whether it is
worth paying: what a call costs, whether the endpoint answered when last probed, and what
its payment record actually shows.

curl -s 'https://api.roundhouseai.io/v0/endpoints?q=api.biotechcatalystsentinel.com'
curl -s 'https://api.roundhouseai.io/v0/merchants/<the payTo wallet returned above>'

Then call it: read the price from the live 402 at https://api.biotechcatalystsentinel.com/v1/catalysts/upcoming, never from
a cached figure, and pay with an x402 client.

The /v0 API needs an API key (`authorization: Bearer rh_live_…`) on everything except
/v0/unified* and /v0/endpoints. Mint a personal key for $0.01 at GET https://api.roundhouseai.io/v0/test/x402,
or use an organization key from https://roundhouseai.io/dashboard/team.

If you do not have Roundhouse tools or skills installed, read
https://roundhouseai.io/skill.md first — it is the whole procedure.