api.biotechcatalystsentinel.com
A machine-first oracle for upcoming FDA PDUFA decision dates, extracted from primary SEC filings and accuracy-backtested against actual FDA decisions. Two paid endpoints over x402 (Base or Solana USDC) — upcoming dates and the catalyst change history; plus a free, auditable accuracy track record.
TradingLiveeip155:8453Exactvia cdp
Calls · 30d
3↓ 28%
This endpoint's own trailing-30-day call count, as published by the upstream catalog and snapshotted daily. 29 snapshots so far.
$1.81
Verified settled volume
62 settlements proven x402 by their on-chain EIP-3009 marker.
$0.050
Listed price
As published in the catalog. Always read the live 402 before paying.
3
Calls · 30d
Upstream's own call count for this endpoint, not ours.
1
Unique payers · 30d
Last called 2026-09-06 10:06Z
—
Upstream on-chain volume
Reported by the source catalog.
Paid to
0xcD8975137D48ED9bfD1C299a62c01420B860070dThe wallet the 402 directs payment to. Its whole payment record — every payer, every chain — is on the merchant page.
Asset 0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913
Provider
The payTo wallet does not resolve to a registered ERC-8004 agent. That is not a verdict on the service — most of the catalog is unregistered.
Live 402 challenge
Captured by the enrichment pass, not read just now. Prices can change — always read the 402 the endpoint answers with.
{
"error": "Payment required",
"accepts": [
{
"asset": "0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913",
"extra": {
"name": "USD Coin",
"version": "2"
},
"payTo": "0xcD8975137D48ED9bfD1C299a62c01420B860070d",
"amount": "50000",
"scheme": "exact",
"network": "eip155:8453",
"maxTimeoutSeconds": 300
},
{
"asset": "EPjFWdd5AufqSSqeM2qN1xzybapC8G4wEGGkZwyTDt1v",
"extra": {
"feePayer": "BENrLoUbndxoNMUS5JXApGMtNykLjFXXixMtpDwDR9SP"
},
"payTo": "3gM4YDDPAi7w1di7rHAAaHc5T1tR7NRXzLWzPPN4ZRaM",
"amount": "50000",
"scheme": "exact",
"network": "solana:5eykt4UsFv8P8NJdTREpY1vzqKqZKvdp",
"maxTimeoutSeconds": 300
}
],
"resource": {
"url": "https://api.biotechcatalystsentinel.com/v1/events",
"mimeType": "application/json",
"description": "FDA drug-approval catalyst change stream for US-listed biotechs: every state change of every tracked catalyst — each PDUFA date as set, extended and resolved — with the real outcome (approval or CRL), the SEC filing quote and its EDGAR source, as a since-cursor delta feed. Use when you mirror the calendar and need date changes and outcomes as they land, not a snapshot. Accuracy AND coverage are free at GET /v1/accuracy. Flat price per request."
},
"extensions": {
"bazaar": {
"info": {
"input": {
"type": "http",
"method": "GET",
"queryParams": {
"limit": 100,
"since": 0
}
},
"output": {
"type": "json",
"example": {
"data": [
{
"ticker": "XSMPL",
"applied": true,
"company": "Sample Therapeutics, Inc.",
"outcome": null,
"tickers": [
"XSMPL",
"XPRTN"
],
"event_id": 990101,
"filed_at": "2025-11-03",
"new_date": "2026-04-18",
"accession": "0009999001-25-000090",
"authority": "llm_high",
"drug_name": "SAMPLIMAB",
"confidence": "high",
"delta_days": null,
"event_type": "new_date_assigned",
"indication": "sample indication (moderate-to-severe examplitis)",
"prior_date": null,
"source_url": "https://www.sec.gov/Archives/edgar/data/9999001/000999900125000090/0009999001-25-000090-index.htm",
"catalyst_id": 990001,
"detected_at": "2025-11-03T13:41:09.000000+00:00",
"merged_into": null,
"date_changed": true,
"days_to_date": null,
"source_quote": "The FDA has assigned a PDUFA target action date of April 18, 2026 for SAMPLIMAB. [FICTIONAL SAMPLE — not a real filing sentence]",
"date_confidence": "confirmed",
"new_date_upcoming": false,
"application_number": "BLA999901"
}
],
"meta": {
"limit": 100,
"total": 1,
"has_more": false,
"next_since": 990106
}
}
}
},
"schema": {
"type": "object",
"$schema": "https://json-schema.org/draft/2020-12/schema",
"required": [
"input"
],
"properties": {
"input": {
"type": "object",
"required": [
"type",
"method"
],
"properties": {
"type": {
"type": "string",
"const": "http"
},
"method": {
"enum": [
"GET",
"HEAD",
"DELETE"
],
"type": "string"
},
"queryParams": {
"type": "object",
"required": [],
"properties": {
"limit": {
"type": "integer",
"default": 100,
"maximum": 500,
"minimum": 1,
"description": "Maximum number of events to return (1-500; default 100)."
},
"since": {
"type": "integer",
"minimum": 0,
"description": "Cursor: return only events with an event_id greater than this (0 = from the start). Pass the last event_id you saw to page forward."
},
"ticker": {
"type": "string",
"pattern": "^\\S+$",
"maxLength": 12,
"minLength": 1,
"description": "Optional server-side filter: only events whose record is filed by this ticker's issuer or exposes it as a co-filer in tickers[] (case-insensitive). Composes with since — limit counts matched events, so a filtered backlog drains without gaps. Unknown ticker returns an empty 200. Does not change the price."
}
}
}
},
"additionalProperties": false
},
"output": {
"type": "object",
"required": [
"type"
],
"properties": {
"type": {
"type": "string"
},
"example": {
"type": "object",
"properties": {
"data": {
"type": "array",
"items": {
"type": "object",
"required": [
"event_id",
"catalyst_id",
"event_type"
],
"properties": {
"ticker": {
"type": [
"string",
"null"
]
},
"applied": {
"type": "boolean"
},
"company": {
"type": [
"string",
"null"
]
},
"outcome": {
"enum": [
"approved",
"tentative",
"crl",
"none_found",
null
],
"type": [
"string",
"null"
]
},
"tickers": {
"type": "array",
"items": {
"type": "string"
}
},
"event_id": {
"type": "integer"
},
"filed_at": {
"type": [
"string",
"null"
]
},
"new_date": {
"type": [
"string",
"null"
]
},
"accession": {
"type": [
"string",
"null"
]
},
"authority": {
"enum": [
"human_lock",
"llm_high",
"regex",
"llm_medium",
"llm_low",
null
],
"type": [
"string",
"null"
]
},
"drug_name": {
"type": [
"string",
"null"
]
},
"confidence": {
"enum": [
"high",
"medium",
"low",
null
],
"type": [
"string",
"null"
]
},
"delta_days": {
"type": [
"integer",
"null"
]
},
"event_type": {
"enum": [
"new_date_assigned",
"date_extension",
"decision_outcome",
"retracted",
"restored",
"corrected"
],
"type": "string"
},
"indication": {
"type": [
"string",
"null"
]
},
"prior_date": {
"type": [
"string",
"null"
]
},
"source_url": {
"type": [
"string",
"null"
]
},
"catalyst_id": {
"type": "integer"
},
"detected_at": {
"type": [
"string",
"null"
]
},
"merged_into": {
"type": [
"integer",
"null"
]
},
"date_changed": {
"type": "boolean"
},
"days_to_date": {
"type": [
"integer",
"null"
]
},
"source_quote": {
"type": [
"string",
"null"
]
},
"date_confidence": {
"enum": [
"confirmed",
"reported",
"estimated",
null
],
"type": [
"string",
"null"
]
},
"new_date_upcoming": {
"type": "boolean"
},
"application_number": {
"type": [
"string",
"null"
]
}
}
},
"description": "One row per state change, oldest-first while draining a `since` cursor. `tickers` lists every co-filer exposed to the decision."
},
"meta": {
"type": "object",
"description": "Result metadata, e.g. total count."
}
}
}
}
}
}
}
}
},
"x402Version": 2
}Accepts
The payment requirements as published to the catalog. Read the live 402 before paying — a price here is a claim, not a quote.
0.05USDC≈ $0.05 USD
on Base · exact scheme
Pay 0.05 USDC on Base to 0xcD89…0070d. The signed payment is good for 5 minutes.
- Paid to
- 0xcD89…0070d
- USD Coin contract
- 0x8335…02913
- Payment window
- 5 minutes
- As published
- 50000 smallest units
50000units
on solana:5eykt4UsFv8P8NJdTREpY1vzqKqZKvdp · exact scheme
That figure is in the token’s smallest units. Roundhouse does not hold this contract’s decimals, so it is shown as published rather than converted.
- Paid to
- 3gM4YD…4ZRaM
- Token contract
- EPjFWd…TDt1v
- Payment window
- 5 minutes
The catalog’s raw entry
[
{
"asset": "0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913",
"extra": {
"name": "USD Coin",
"version": "2"
},
"payTo": "0xcD8975137D48ED9bfD1C299a62c01420B860070d",
"amount": "50000",
"scheme": "exact",
"network": "eip155:8453",
"maxTimeoutSeconds": 300
},
{
"asset": "EPjFWdd5AufqSSqeM2qN1xzybapC8G4wEGGkZwyTDt1v",
"extra": {
"feePayer": "BENrLoUbndxoNMUS5JXApGMtNykLjFXXixMtpDwDR9SP"
},
"payTo": "3gM4YDDPAi7w1di7rHAAaHc5T1tR7NRXzLWzPPN4ZRaM",
"amount": "50000",
"scheme": "exact",
"network": "solana:5eykt4UsFv8P8NJdTREpY1vzqKqZKvdp",
"maxTimeoutSeconds": 300
}
]Extensions
{
"bazaar": {
"info": {
"input": {
"type": "http",
"method": "GET",
"queryParams": {
"limit": 100,
"since": 0
}
},
"output": {
"type": "json",
"example": {
"data": [
{
"ticker": "XSMPL",
"applied": true,
"company": "Sample Therapeutics, Inc.",
"outcome": null,
"tickers": [
"XSMPL",
"XPRTN"
],
"event_id": 990101,
"filed_at": "2025-11-03",
"new_date": "2026-04-18",
"accession": "0009999001-25-000090",
"authority": "llm_high",
"drug_name": "SAMPLIMAB",
"confidence": "high",
"delta_days": null,
"event_type": "new_date_assigned",
"indication": "sample indication (moderate-to-severe examplitis)",
"prior_date": null,
"source_url": "https://www.sec.gov/Archives/edgar/data/9999001/000999900125000090/0009999001-25-000090-index.htm",
"catalyst_id": 990001,
"detected_at": "2025-11-03T13:41:09.000000+00:00",
"merged_into": null,
"date_changed": true,
"days_to_date": null,
"source_quote": "The FDA has assigned a PDUFA target action date of April 18, 2026 for SAMPLIMAB. [FICTIONAL SAMPLE — not a real filing sentence]",
"date_confidence": "confirmed",
"new_date_upcoming": false,
"application_number": "BLA999901"
}
],
"meta": {
"limit": 100,
"total": 1,
"has_more": false,
"next_since": 990106
}
}
}
},
"schema": {
"type": "object",
"$schema": "https://json-schema.org/draft/2020-12/schema",
"required": [
"input"
],
"properties": {
"input": {
"type": "object",
"required": [
"type",
"method"
],
"properties": {
"type": {
"type": "string",
"const": "http"
},
"method": {
"enum": [
"GET",
"HEAD",
"DELETE"
],
"type": "string"
},
"queryParams": {
"type": "object",
"required": [],
"properties": {
"limit": {
"type": "integer",
"default": 100,
"maximum": 500,
"minimum": 1,
"description": "Maximum number of events to return (1-500; default 100)."
},
"since": {
"type": "integer",
"minimum": 0,
"description": "Cursor: return only events with an event_id greater than this (0 = from the start). Pass the last event_id you saw to page forward."
},
"ticker": {
"type": "string",
"pattern": "^\\S+$",
"maxLength": 12,
"minLength": 1,
"description": "Optional server-side filter: only events whose record is filed by this ticker's issuer or exposes it as a co-filer in tickers[] (case-insensitive). Composes with since — limit counts matched events, so a filtered backlog drains without gaps. Unknown ticker returns an empty 200. Does not change the price."
}
}
}
},
"additionalProperties": false
},
"output": {
"type": "object",
"required": [
"type"
],
"properties": {
"type": {
"type": "string"
},
"example": {
"type": "object",
"properties": {
"data": {
"type": "array",
"items": {
"type": "object",
"required": [
"event_id",
"catalyst_id",
"event_type"
],
"properties": {
"ticker": {
"type": [
"string",
"null"
]
},
"applied": {
"type": "boolean"
},
"company": {
"type": [
"string",
"null"
]
},
"outcome": {
"enum": [
"approved",
"tentative",
"crl",
"none_found",
null
],
"type": [
"string",
"null"
]
},
"tickers": {
"type": "array",
"items": {
"type": "string"
}
},
"event_id": {
"type": "integer"
},
"filed_at": {
"type": [
"string",
"null"
]
},
"new_date": {
"type": [
"string",
"null"
]
},
"accession": {
"type": [
"string",
"null"
]
},
"authority": {
"enum": [
"human_lock",
"llm_high",
"regex",
"llm_medium",
"llm_low",
null
],
"type": [
"string",
"null"
]
},
"drug_name": {
"type": [
"string",
"null"
]
},
"confidence": {
"enum": [
"high",
"medium",
"low",
null
],
"type": [
"string",
"null"
]
},
"delta_days": {
"type": [
"integer",
"null"
]
},
"event_type": {
"enum": [
"new_date_assigned",
"date_extension",
"decision_outcome",
"retracted",
"restored",
"corrected"
],
"type": "string"
},
"indication": {
"type": [
"string",
"null"
]
},
"prior_date": {
"type": [
"string",
"null"
]
},
"source_url": {
"type": [
"string",
"null"
]
},
"catalyst_id": {
"type": "integer"
},
"detected_at": {
"type": [
"string",
"null"
]
},
"merged_into": {
"type": [
"integer",
"null"
]
},
"date_changed": {
"type": "boolean"
},
"days_to_date": {
"type": [
"integer",
"null"
]
},
"source_quote": {
"type": [
"string",
"null"
]
},
"date_confidence": {
"enum": [
"confirmed",
"reported",
"estimated",
null
],
"type": [
"string",
"null"
]
},
"new_date_upcoming": {
"type": "boolean"
},
"application_number": {
"type": [
"string",
"null"
]
}
}
},
"description": "One row per state change, oldest-first while draining a `since` cursor. `tickers` lists every co-filer exposed to the decision."
},
"meta": {
"type": "object",
"description": "Result metadata, e.g. total count."
}
}
}
}
}
}
}
}
}Provenance
- Seen in the source catalog
- 2026-09-06 10:06Z
- Last indexed by Roundhouse
- 2026-09-25 01:50Z
- Last enriched (probe, favicon, geo)
- 2026-09-22 09:15Z
- x402 version
- 2
- Max timeout
- 300s
- Liveness probe
- HTTP 402
Hand this page to an agent
Copy the prompt and paste it into Claude, an MCP client or your own agent — it will vet this service and call it over the free read API. No key, no account.
GET api.roundhouseai.io/v0/endpoints
This endpoint's own trailing-30-day call count, as published by the upstream catalog and snapshotted daily. 29 snapshots so far. Verified volume counts only settlements with an on-chain EIP-3009 marker.
Show the promptHide the prompt
Using Roundhouse, look up the x402 service api.biotechcatalystsentinel.com and tell me whether it is worth paying: what a call costs, whether the endpoint answered when last probed, and what its payment record actually shows. curl -s 'https://api.roundhouseai.io/v0/endpoints?q=api.biotechcatalystsentinel.com' curl -s 'https://api.roundhouseai.io/v0/merchants/<the payTo wallet returned above>' Then call it: read the price from the live 402 at https://api.biotechcatalystsentinel.com/v1/events, never from a cached figure, and pay with an x402 client. The /v0 API needs an API key (`authorization: Bearer rh_live_…`) on everything except /v0/unified* and /v0/endpoints. Mint a personal key for $0.01 at GET https://api.roundhouseai.io/v0/test/x402, or use an organization key from https://roundhouseai.io/dashboard/team. If you do not have Roundhouse tools or skills installed, read https://roundhouseai.io/skill.md first — it is the whole procedure.