magent

Live 402 challenge

Captured by the enrichment pass, not read just now. Prices can change — always read the 402 the endpoint answers with.

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        "paymentFlow": "upfront",
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  "resource": {
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    "tags": [
      "mcdonald-2024",
      "multiple-sclerosis",
      "neurology",
      "cis",
      "calculator"
    ],
    "mimeType": "application/json",
    "description": "2024 McDonald typical CIS (Montalban 2025). mcdonald_ms iff typical_cis and no_better_explanation and: ≥2 attacks with ≥2 lesions; or ≥2 attacks with one lesion plus DIS; or CIS with ≥2 lesions plus MRI DIT, OCB, or kappa FLC; or CIS with one lesion plus DIS and MRI DIT, OCB, or kappa FLC. DIS = ≥2 of 5 topographies (optic nerve added). Kappa FLC interchangeable with OCB. Not 2017 McDonald. Not PPMS. Not RIS. magent does not read MRI or assay CSF. Not a diagnosis. Not a medical device.",
    "serviceName": "magent"
  },
  "extensions": {
    "bazaar": {
      "info": {
        "input": {
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          "method": "GET",
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            "csf_kflc": false,
            "optic_nerve": false,
            "spinal_cord": false,
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            "infratentorial": false,
            "periventricular": false,
            "csf_specific_ocb": false,
            "two_or_more_attacks": true,
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            "no_better_explanation": true,
            "cortical_or_juxtacortical": false
          }
        },
        "output": {
          "type": "json",
          "example": {
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            "dit_mri": false,
            "formula": "mcdonald_2024",
            "citation": {
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                "met": true,
                "factor": "typical_cis"
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              {
                "met": true,
                "factor": "no_better_explanation"
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              {
                "met": true,
                "factor": "two_or_more_attacks"
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              {
                "met": true,
                "factor": "two_or_more_lesions"
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              {
                "met": false,
                "factor": "periventricular"
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              {
                "met": false,
                "factor": "cortical_or_juxtacortical"
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              {
                "met": false,
                "factor": "infratentorial"
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              {
                "met": false,
                "factor": "spinal_cord"
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              {
                "met": false,
                "factor": "optic_nerve"
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              {
                "met": false,
                "factor": "dis"
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              {
                "met": false,
                "factor": "dit_mri"
              },
              {
                "met": false,
                "factor": "csf_specific_ocb"
              },
              {
                "met": false,
                "factor": "csf_kflc"
              },
              {
                "met": true,
                "factor": "relapsing_cis_pathway"
              },
              {
                "met": true,
                "factor": "mcdonald_ms"
              }
            ],
            "csf_kflc": false,
            "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
            "mcdonald_ms": true,
            "optic_nerve": false,
            "spinal_cord": false,
            "typical_cis": true,
            "infratentorial": false,
            "periventricular": false,
            "csf_specific_ocb": false,
            "formula_expression": "mcdonald_ms iff typical_cis and no_better_explanation and ((two_or_more_attacks and two_or_more_lesions) or (two_or_more_attacks and not two_or_more_lesions and dis) or (not two_or_more_attacks and two_or_more_lesions and (dit_mri or csf_specific_ocb or csf_kflc)) or (not two_or_more_attacks and not two_or_more_lesions and dis and (dit_mri or csf_specific_ocb or csf_kflc))) (Montalban 2025 / 2024 McDonald typical CIS). dis is true iff at least two of periventricular, cortical_or_juxtacortical, infratentorial, spinal_cord, optic_nerve are true. CSF kappa free-light chains are interchangeable with CSF-specific OCB as the CSF DIT substitute. Not PPMS. Not RIS. Not 2017 McDonald. magent does not read MRI, OCT, VEP, or assay CSF. Not a diagnosis",
            "two_or_more_attacks": true,
            "two_or_more_lesions": true,
            "no_better_explanation": true,
            "cortical_or_juxtacortical": false
          }
        },
        "iconUrl": "https://api.magentlab.com/favicon.ico"
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      "schema": {
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        "required": [
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            "required": [
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              "method"
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            "properties": {
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                "const": "http"
              },
              "method": {
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                  "HEAD",
                  "DELETE"
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                "type": "string"
              },
              "headers": {
                "type": "object",
                "additionalProperties": {
                  "type": "string"
                }
              },
              "queryParams": {
                "type": "object",
                "required": [
                  "typical_cis",
                  "no_better_explanation",
                  "two_or_more_attacks",
                  "two_or_more_lesions",
                  "periventricular",
                  "cortical_or_juxtacortical",
                  "infratentorial",
                  "spinal_cord",
                  "optic_nerve",
                  "dit_mri",
                  "csf_specific_ocb",
                  "csf_kflc"
                ],
                "properties": {
                  "dit_mri": {
                    "type": "boolean",
                    "description": "MRI dissemination in time as assigned by the caller (simultaneous Gd-enhancing and non-enhancing lesions, or a new T2 or Gd-enhancing lesion on follow-up vs baseline). true or false. magent does not read MRI."
                  },
                  "csf_kflc": {
                    "type": "boolean",
                    "description": "CSF kappa free-light chains positive as assigned by the caller (2024: interchangeable with oligoclonal bands as the CSF DIT marker). Caller-assigned flag only; this tool does not apply a numeric kFLC index cutoff. true or false. magent does not assay CSF."
                  },
                  "optic_nerve": {
                    "type": "boolean",
                    "description": "Caller-assigned typical optic-nerve topography (fifth 2024 DIS location; Montalban 2025). true or false. magent does not read MRI, OCT, or VEP."
                  },
                  "spinal_cord": {
                    "type": "boolean",
                    "description": "Caller-assigned typical spinal-cord MS lesion topography (one of five 2024 DIS locations). true or false. magent does not read MRI."
                  },
                  "typical_cis": {
                    "type": "boolean",
                    "description": "Typical clinically isolated syndrome as assigned by the caller (Montalban 2025 typical CIS / relapsing pathway). If false, mcdonald_ms is false; this tool does not diagnose MS from atypical presentations, PPMS, or RIS. true or false. magent does not examine the patient."
                  },
                  "infratentorial": {
                    "type": "boolean",
                    "description": "Caller-assigned typical infratentorial MS lesion topography (one of five 2024 DIS locations). true or false. magent does not read MRI."
                  },
                  "periventricular": {
                    "type": "boolean",
                    "description": "Caller-assigned typical periventricular MS lesion topography (one of five 2024 DIS locations). true or false. magent does not read MRI."
                  },
                  "csf_specific_ocb": {
                    "type": "boolean",
                    "description": "CSF-specific oligoclonal bands as assigned by the caller (2024 DIT substitute; interchangeable with kappa free-light chains). true or false. magent does not assay CSF."
                  },
                  "two_or_more_attacks": {
                    "type": "boolean",
                    "description": "≥2 clinical attacks as assigned by the caller. true means two or more attacks; false means this is the first/CIS attack. true or false. magent does not date attacks."
                  },
                  "two_or_more_lesions": {
                    "type": "boolean",
                    "description": "Objective clinical evidence of ≥2 lesions as assigned by the caller. true means ≥2 lesions; false means 1 lesion. true or false. magent does not examine the patient."
                  },
                  "no_better_explanation": {
                    "type": "boolean",
                    "description": "No better explanation for the presentation as assigned by the caller (Montalban 2025). If false, mcdonald_ms is false. Remain vigilant for NMOSD. true or false. magent does not assign a better explanation."
                  },
                  "cortical_or_juxtacortical": {
                    "type": "boolean",
                    "description": "Caller-assigned typical cortical or juxtacortical MS lesion topography (one of five 2024 DIS locations). true or false. magent does not read MRI."
                  }
                }
              }
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              "example": {
                "type": "object"
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            }
          }
        }
      }
    }
  },
  "x402Version": 2
}

Accepts

The payment requirements as published to the catalog. Read the live 402 before paying — a price here is a claim, not a quote.

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Extensions

{
  "bazaar": {
    "info": {
      "input": {
        "body": {
          "items": [
            {
              "dit_mri": false,
              "csf_kflc": false,
              "optic_nerve": false,
              "spinal_cord": false,
              "typical_cis": true,
              "infratentorial": false,
              "periventricular": false,
              "csf_specific_ocb": false,
              "two_or_more_attacks": true,
              "two_or_more_lesions": true,
              "no_better_explanation": true,
              "cortical_or_juxtacortical": false
            },
            {
              "dit_mri": false,
              "csf_kflc": false,
              "optic_nerve": false,
              "spinal_cord": false,
              "typical_cis": true,
              "infratentorial": false,
              "periventricular": false,
              "csf_specific_ocb": false,
              "two_or_more_attacks": true,
              "two_or_more_lesions": true,
              "no_better_explanation": true,
              "cortical_or_juxtacortical": false
            }
          ]
        },
        "type": "http",
        "method": "POST"
      },
      "output": {
        "type": "json",
        "example": {
          "path": "/api/calc/mcdonald_2024",
          "count": 2,
          "items": [
            {
              "dis": false,
              "dit_mri": false,
              "formula": "mcdonald_2024",
              "citation": {
                "id": "montalban-2025",
                "doi": "10.1016/S1474-4422(25)00270-4",
                "pmid": "40975101",
                "title": "Diagnosis of multiple sclerosis: 2024 revisions of the McDonald criteria",
                "source": "Lancet Neurol. 2025;24(10):850-865",
                "authors": "Montalban X, Lebrun-Frénay C, Oh J, et al."
              },
              "criteria": [
                {
                  "met": true,
                  "factor": "typical_cis"
                },
                {
                  "met": true,
                  "factor": "no_better_explanation"
                },
                {
                  "met": true,
                  "factor": "two_or_more_attacks"
                },
                {
                  "met": true,
                  "factor": "two_or_more_lesions"
                },
                {
                  "met": false,
                  "factor": "periventricular"
                },
                {
                  "met": false,
                  "factor": "cortical_or_juxtacortical"
                },
                {
                  "met": false,
                  "factor": "infratentorial"
                },
                {
                  "met": false,
                  "factor": "spinal_cord"
                },
                {
                  "met": false,
                  "factor": "optic_nerve"
                },
                {
                  "met": false,
                  "factor": "dis"
                },
                {
                  "met": false,
                  "factor": "dit_mri"
                },
                {
                  "met": false,
                  "factor": "csf_specific_ocb"
                },
                {
                  "met": false,
                  "factor": "csf_kflc"
                },
                {
                  "met": true,
                  "factor": "relapsing_cis_pathway"
                },
                {
                  "met": true,
                  "factor": "mcdonald_ms"
                }
              ],
              "csf_kflc": false,
              "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
              "mcdonald_ms": true,
              "optic_nerve": false,
              "spinal_cord": false,
              "typical_cis": true,
              "infratentorial": false,
              "periventricular": false,
              "csf_specific_ocb": false,
              "formula_expression": "mcdonald_ms iff typical_cis and no_better_explanation and ((two_or_more_attacks and two_or_more_lesions) or (two_or_more_attacks and not two_or_more_lesions and dis) or (not two_or_more_attacks and two_or_more_lesions and (dit_mri or csf_specific_ocb or csf_kflc)) or (not two_or_more_attacks and not two_or_more_lesions and dis and (dit_mri or csf_specific_ocb or csf_kflc))) (Montalban 2025 / 2024 McDonald typical CIS). dis is true iff at least two of periventricular, cortical_or_juxtacortical, infratentorial, spinal_cord, optic_nerve are true. CSF kappa free-light chains are interchangeable with CSF-specific OCB as the CSF DIT substitute. Not PPMS. Not RIS. Not 2017 McDonald. magent does not read MRI, OCT, VEP, or assay CSF. Not a diagnosis",
              "two_or_more_attacks": true,
              "two_or_more_lesions": true,
              "no_better_explanation": true,
              "cortical_or_juxtacortical": false
            },
            {
              "dis": false,
              "dit_mri": false,
              "formula": "mcdonald_2024",
              "citation": {
                "id": "montalban-2025",
                "doi": "10.1016/S1474-4422(25)00270-4",
                "pmid": "40975101",
                "title": "Diagnosis of multiple sclerosis: 2024 revisions of the McDonald criteria",
                "source": "Lancet Neurol. 2025;24(10):850-865",
                "authors": "Montalban X, Lebrun-Frénay C, Oh J, et al."
              },
              "criteria": [
                {
                  "met": true,
                  "factor": "typical_cis"
                },
                {
                  "met": true,
                  "factor": "no_better_explanation"
                },
                {
                  "met": true,
                  "factor": "two_or_more_attacks"
                },
                {
                  "met": true,
                  "factor": "two_or_more_lesions"
                },
                {
                  "met": false,
                  "factor": "periventricular"
                },
                {
                  "met": false,
                  "factor": "cortical_or_juxtacortical"
                },
                {
                  "met": false,
                  "factor": "infratentorial"
                },
                {
                  "met": false,
                  "factor": "spinal_cord"
                },
                {
                  "met": false,
                  "factor": "optic_nerve"
                },
                {
                  "met": false,
                  "factor": "dis"
                },
                {
                  "met": false,
                  "factor": "dit_mri"
                },
                {
                  "met": false,
                  "factor": "csf_specific_ocb"
                },
                {
                  "met": false,
                  "factor": "csf_kflc"
                },
                {
                  "met": true,
                  "factor": "relapsing_cis_pathway"
                },
                {
                  "met": true,
                  "factor": "mcdonald_ms"
                }
              ],
              "csf_kflc": false,
              "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
              "mcdonald_ms": true,
              "optic_nerve": false,
              "spinal_cord": false,
              "typical_cis": true,
              "infratentorial": false,
              "periventricular": false,
              "csf_specific_ocb": false,
              "formula_expression": "mcdonald_ms iff typical_cis and no_better_explanation and ((two_or_more_attacks and two_or_more_lesions) or (two_or_more_attacks and not two_or_more_lesions and dis) or (not two_or_more_attacks and two_or_more_lesions and (dit_mri or csf_specific_ocb or csf_kflc)) or (not two_or_more_attacks and not two_or_more_lesions and dis and (dit_mri or csf_specific_ocb or csf_kflc))) (Montalban 2025 / 2024 McDonald typical CIS). dis is true iff at least two of periventricular, cortical_or_juxtacortical, infratentorial, spinal_cord, optic_nerve are true. CSF kappa free-light chains are interchangeable with CSF-specific OCB as the CSF DIT substitute. Not PPMS. Not RIS. Not 2017 McDonald. magent does not read MRI, OCT, VEP, or assay CSF. Not a diagnosis",
              "two_or_more_attacks": true,
              "two_or_more_lesions": true,
              "no_better_explanation": true,
              "cortical_or_juxtacortical": false
            }
          ]
        }
      },
      "iconUrl": "https://api.magentlab.com/favicon.ico"
    },
    "schema": {
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      "$schema": "https://json-schema.org/draft/2020-12/schema",
      "required": [
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      "properties": {
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          "required": [
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            "method"
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          "properties": {
            "body": {
              "type": "object",
              "required": [
                "items"
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              "properties": {
                "items": {
                  "type": "array",
                  "items": {
                    "type": "object",
                    "required": [
                      "typical_cis",
                      "no_better_explanation",
                      "two_or_more_attacks",
                      "two_or_more_lesions",
                      "periventricular",
                      "cortical_or_juxtacortical",
                      "infratentorial",
                      "spinal_cord",
                      "optic_nerve",
                      "dit_mri",
                      "csf_specific_ocb",
                      "csf_kflc"
                    ],
                    "properties": {
                      "dit_mri": {
                        "type": "boolean",
                        "description": "MRI dissemination in time as assigned by the caller (simultaneous Gd-enhancing and non-enhancing lesions, or a new T2 or Gd-enhancing lesion on follow-up vs baseline). true or false. magent does not read MRI."
                      },
                      "csf_kflc": {
                        "type": "boolean",
                        "description": "CSF kappa free-light chains positive as assigned by the caller (2024: interchangeable with oligoclonal bands as the CSF DIT marker). Caller-assigned flag only; this tool does not apply a numeric kFLC index cutoff. true or false. magent does not assay CSF."
                      },
                      "optic_nerve": {
                        "type": "boolean",
                        "description": "Caller-assigned typical optic-nerve topography (fifth 2024 DIS location; Montalban 2025). true or false. magent does not read MRI, OCT, or VEP."
                      },
                      "spinal_cord": {
                        "type": "boolean",
                        "description": "Caller-assigned typical spinal-cord MS lesion topography (one of five 2024 DIS locations). true or false. magent does not read MRI."
                      },
                      "typical_cis": {
                        "type": "boolean",
                        "description": "Typical clinically isolated syndrome as assigned by the caller (Montalban 2025 typical CIS / relapsing pathway). If false, mcdonald_ms is false; this tool does not diagnose MS from atypical presentations, PPMS, or RIS. true or false. magent does not examine the patient."
                      },
                      "infratentorial": {
                        "type": "boolean",
                        "description": "Caller-assigned typical infratentorial MS lesion topography (one of five 2024 DIS locations). true or false. magent does not read MRI."
                      },
                      "periventricular": {
                        "type": "boolean",
                        "description": "Caller-assigned typical periventricular MS lesion topography (one of five 2024 DIS locations). true or false. magent does not read MRI."
                      },
                      "csf_specific_ocb": {
                        "type": "boolean",
                        "description": "CSF-specific oligoclonal bands as assigned by the caller (2024 DIT substitute; interchangeable with kappa free-light chains). true or false. magent does not assay CSF."
                      },
                      "two_or_more_attacks": {
                        "type": "boolean",
                        "description": "≥2 clinical attacks as assigned by the caller. true means two or more attacks; false means this is the first/CIS attack. true or false. magent does not date attacks."
                      },
                      "two_or_more_lesions": {
                        "type": "boolean",
                        "description": "Objective clinical evidence of ≥2 lesions as assigned by the caller. true means ≥2 lesions; false means 1 lesion. true or false. magent does not examine the patient."
                      },
                      "no_better_explanation": {
                        "type": "boolean",
                        "description": "No better explanation for the presentation as assigned by the caller (Montalban 2025). If false, mcdonald_ms is false. Remain vigilant for NMOSD. true or false. magent does not assign a better explanation."
                      },
                      "cortical_or_juxtacortical": {
                        "type": "boolean",
                        "description": "Caller-assigned typical cortical or juxtacortical MS lesion topography (one of five 2024 DIS locations). true or false. magent does not read MRI."
                      }
                    }
                  },
                  "maxItems": 25,
                  "minItems": 1
                }
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              "additionalProperties": false
            },
            "type": {
              "type": "string",
              "const": "http"
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              "const": "POST"
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              "additionalProperties": {
                "type": "string"
              }
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    }
  }
}

Provenance

Seen in the source catalog

2026-09-02 20:05Z

Last indexed by Roundhouse

2026-09-07 06:20Z

Last enriched (probe, favicon, geo)

2026-09-11 12:16Z

x402 version

2

Max timeout

600s

Liveness probe

HTTP 0