Clinical Trial Search

Clinical trial search — find ClinicalTrials.gov studies by free text, condition, intervention, sponsor, recruitment status and phase, and get each study's NCT id, titles, status, phases, conditions, interventions, sponsor, start and completion dates, enrollment and whether results are posted. Use for drug development, medical research and patient-recruitment questions.

SearchLiveeip155:8453Exactvia cdp
Clinical-trialsClinicaltrials-govTrial-searchMedical-researchDrug-development
Calls · 30d
2
This endpoint's own trailing-30-day call count, as published by the upstream catalog and snapshotted daily. 5 snapshots so far.
$31.40
Verified settled volume
1,705 settlements proven x402 by their on-chain EIP-3009 marker.
$0.010
Listed price
As published in the catalog. Always read the live 402 before paying.
2
Calls · 30d
Upstream's own call count for this endpoint, not ours.
2
Unique payers · 30d
Last called 2026-10-20 21:12Z
—
Upstream on-chain volume
Reported by the source catalog.
Paid to
0x8C128f1Ee62Bb5e47867CfbAe2ad89be325Df1b2

The wallet the 402 directs payment to. Its whole payment record — every payer, every chain — is on the merchant page.

Asset 0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913

Provider

The payTo wallet does not resolve to a registered ERC-8004 agent. That is not a verdict on the service — most of the catalog is unregistered.

Live 402 challenge

Captured by the enrichment pass, not read just now. Prices can change — always read the 402 the endpoint answers with.

{
  "hint": "This endpoint requires x402 payment. The price and payment options are in the PAYMENT-REQUIRED response header (x402 v2). Pay with an x402 client, then retry to receive the data.",
  "llms": "https://clinical-trials.use.x402atlas.com/llms.txt",
  "error": "payment_required",
  "price": "$0.01 per call",
  "method": "GET",
  "accepts": [
    {
      "asset": "0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913",
      "extra": {
        "name": "USD Coin",
        "tier": "standard",
        "version": "2",
        "merchant": "x402Atlas"
      },
      "payTo": "0x8C128f1Ee62Bb5e47867CfbAe2ad89be325Df1b2",
      "amount": "10000",
      "scheme": "exact",
      "network": "eip155:8453",
      "maxTimeoutSeconds": 300
    },
    {
      "asset": "0x3c499c542cEF5E3811e1192ce70d8cC03d5c3359",
      "extra": {
        "name": "USD Coin",
        "tier": "standard",
        "version": "2",
        "merchant": "x402Atlas"
      },
      "payTo": "0x8C128f1Ee62Bb5e47867CfbAe2ad89be325Df1b2",
      "amount": "10000",
      "scheme": "exact",
      "network": "eip155:137",
      "maxTimeoutSeconds": 300
    },
    {
      "asset": "0xaf88d065e77c8cC2239327C5EDb3A432268e5831",
      "extra": {
        "name": "USD Coin",
        "tier": "standard",
        "version": "2",
        "merchant": "x402Atlas"
      },
      "payTo": "0x8C128f1Ee62Bb5e47867CfbAe2ad89be325Df1b2",
      "amount": "10000",
      "scheme": "exact",
      "network": "eip155:42161",
      "maxTimeoutSeconds": 300
    },
    {
      "asset": "EPjFWdd5AufqSSqeM2qN1xzybapC8G4wEGGkZwyTDt1v",
      "extra": {
        "tier": "standard",
        "feePayer": "BFK9TLC3edb13K6v4YyH3DwPb5DSUpkWvb7XnqCL9b4F",
        "merchant": "x402Atlas"
      },
      "payTo": "ASt6xvRyQ7ntERsmcYVMdLqZvz1GEN8Fzexzq62tXrNQ",
      "amount": "10000",
      "scheme": "exact",
      "network": "solana:5eykt4UsFv8P8NJdTREpY1vzqKqZKvdp",
      "maxTimeoutSeconds": 300
    }
  ],
  "contact": {
    "email": "support@x402atlas.com"
  },
  "openapi": "https://clinical-trials.use.x402atlas.com/openapi.json",
  "resource": {
    "url": "https://clinical-trials.use.x402atlas.com/search",
    "tags": [
      "clinical-trials",
      "clinicaltrials-gov",
      "trial-search",
      "medical-research",
      "drug-development"
    ],
    "mimeType": "application/json",
    "description": "Clinical trial search — find ClinicalTrials.gov studies by free text, condition, intervention, sponsor, recruitment status and phase, and get each study's NCT id, titles, status, phases, conditions, interventions, sponsor, start and completion dates, enrollment and whether results are posted. Use for drug development, medical research and patient-recruitment questions.",
    "serviceName": "Clinical Trial Search"
  },
  "x402Version": 2,
  "documentation": "https://clinical-trials.use.x402atlas.com/docs"
}

Accepts

The payment requirements as published to the catalog. Read the live 402 before paying — a price here is a claim, not a quote.

0.01USDC≈ $0.01 USD
on Base · exact scheme

Pay 0.01 USDC on Base to 0x8C12…Df1b2. The signed payment is good for 5 minutes.

USD Coin contract
0x8335…02913
Payment window
5 minutes
As published
10000 smallest units
10000units
on Polygon · exact scheme

That figure is in the token’s smallest units. Roundhouse does not hold this contract’s decimals, so it is shown as published rather than converted.

Token contract
0x3c49…c3359
Payment window
5 minutes
10000units
on Arbitrum · exact scheme

That figure is in the token’s smallest units. Roundhouse does not hold this contract’s decimals, so it is shown as published rather than converted.

Token contract
0xaf88…e5831
Payment window
5 minutes
10000units
on solana:5eykt4UsFv8P8NJdTREpY1vzqKqZKvdp · exact scheme

That figure is in the token’s smallest units. Roundhouse does not hold this contract’s decimals, so it is shown as published rather than converted.

Token contract
EPjFWd…TDt1v
Payment window
5 minutes
The catalog’s raw entry
[
  {
    "asset": "0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913",
    "extra": {
      "name": "USD Coin",
      "tier": "standard",
      "version": "2",
      "merchant": "x402Atlas"
    },
    "payTo": "0x8C128f1Ee62Bb5e47867CfbAe2ad89be325Df1b2",
    "amount": "10000",
    "scheme": "exact",
    "network": "eip155:8453",
    "maxTimeoutSeconds": 300
  },
  {
    "asset": "0x3c499c542cEF5E3811e1192ce70d8cC03d5c3359",
    "extra": {
      "name": "USD Coin",
      "tier": "standard",
      "version": "2",
      "merchant": "x402Atlas"
    },
    "payTo": "0x8C128f1Ee62Bb5e47867CfbAe2ad89be325Df1b2",
    "amount": "10000",
    "scheme": "exact",
    "network": "eip155:137",
    "maxTimeoutSeconds": 300
  },
  {
    "asset": "0xaf88d065e77c8cC2239327C5EDb3A432268e5831",
    "extra": {
      "name": "USD Coin",
      "tier": "standard",
      "version": "2",
      "merchant": "x402Atlas"
    },
    "payTo": "0x8C128f1Ee62Bb5e47867CfbAe2ad89be325Df1b2",
    "amount": "10000",
    "scheme": "exact",
    "network": "eip155:42161",
    "maxTimeoutSeconds": 300
  },
  {
    "asset": "EPjFWdd5AufqSSqeM2qN1xzybapC8G4wEGGkZwyTDt1v",
    "extra": {
      "tier": "standard",
      "feePayer": "BFK9TLC3edb13K6v4YyH3DwPb5DSUpkWvb7XnqCL9b4F",
      "merchant": "x402Atlas"
    },
    "payTo": "ASt6xvRyQ7ntERsmcYVMdLqZvz1GEN8Fzexzq62tXrNQ",
    "amount": "10000",
    "scheme": "exact",
    "network": "solana:5eykt4UsFv8P8NJdTREpY1vzqKqZKvdp",
    "maxTimeoutSeconds": 300
  }
]

Extensions

{
  "bazaar": {
    "info": {
      "input": {
        "type": "http",
        "method": "GET",
        "queryParams": {
          "query": "semaglutide",
          "status": "recruiting"
        }
      },
      "output": {
        "type": "json",
        "example": {
          "as_of": "2026-10-20T19:30:00Z",
          "count": 3,
          "phase": "",
          "query": "semaglutide",
          "total": 180,
          "caveat": "Registry entries are sponsor-reported and revised over time; a completed status does not mean results were posted. Not medical advice.",
          "source": {
            "url": "https://clinicaltrials.gov",
            "name": "ClinicalTrials.gov",
            "citation": "Source: ClinicalTrials.gov, U.S. National Library of Medicine. Normalized by x402 Atlas; not the registry's verbatim record."
          },
          "status": [
            "recruiting"
          ],
          "sponsor": "",
          "studies": [
            {
              "url": "https://clinicaltrials.gov/study/NCT05501483",
              "title": "Adipose Tissue Heterogeneity and Its Link to Type 2 Diabetes",
              "nct_id": "NCT05501483",
              "phases": [
                "na"
              ],
              "status": "recruiting",
              "conditions": [
                "Type 2 Diabetes"
              ],
              "enrollment": {
                "type": "estimated",
                "count": 60
              },
              "start_date": {
                "date": "2023-02-08",
                "precision": "day"
              },
              "study_type": "interventional",
              "has_results": false,
              "first_posted": {
                "date": "2022-08-15",
                "precision": "day"
              },
              "last_updated": {
                "date": "2025-02-26",
                "precision": "day"
              },
              "lead_sponsor": "Karolinska Institutet",
              "interventions": [
                {
                  "name": "Pioglitazone 45 mg",
                  "type": "drug"
                },
                {
                  "name": "Empagliflozin 25 MG",
                  "type": "drug"
                },
                {
                  "name": "Semaglutide 7 MG",
                  "type": "drug"
                }
              ],
              "official_title": "Adipose Tissue Heterogeneity and Its Link to Type 2 Diabetes: A Randomized Open Intervention Study That Compares Empagliflozin, Pioglitazone and Semaglutide",
              "completion_date": {
                "date": "2032-12-31",
                "precision": "day"
              },
              "primary_completion_date": {
                "date": "2026-09-01",
                "precision": "day"
              }
            },
            {
              "url": "https://clinicaltrials.gov/study/NCT07213466",
              "title": "Individualized Pharmacological Approach to Obesity in Patients With Bipolar Disorder",
              "nct_id": "NCT07213466",
              "phases": [
                "4"
              ],
              "status": "recruiting",
              "conditions": [
                "Bipolar I Disorder",
                "Bipolar II Disorder",
                "Schizo Affective Disorder",
                "Obesity",
                "Weight Loss",
                "GLP - 1"
              ],
              "enrollment": {
                "type": "estimated",
                "count": 100
              },
              "start_date": {
                "date": "2026-01-19",
                "precision": "day"
              },
              "study_type": "interventional",
              "has_results": false,
              "first_posted": {
                "date": "2025-10-09",
                "precision": "day"
              },
              "last_updated": {
                "date": "2026-03-11",
                "precision": "day"
              },
              "lead_sponsor": "Mayo Clinic",
              "interventions": [
                {
                  "name": "Group Therapy Program",
                  "type": "behavioral"
                },
                {
                  "name": "semaglutide",
                  "type": "drug"
                },
                {
                  "name": "Phentermine-Topiramate",
                  "type": "drug"
                },
                {
                  "name": "naltrexone and bupropion (combination)",
                  "type": "drug"
                }
              ],
              "official_title": "Individualized Pharmacological Approach to Obesity in Patients With Bipolar Disorder - OBOE-Mayo",
              "completion_date": {
                "date": "2029-02-01",
                "precision": "day"
              },
              "primary_completion_date": {
                "date": "2028-02-01",
                "precision": "day"
              }
            },
            {
              "url": "https://clinicaltrials.gov/study/NCT07589322",
              "title": "Comparative Observation of Metabolic and Pharmacologic Adipose Remodeling With Enhanced Incretin AgonisTs",
              "nct_id": "NCT07589322",
              "phases": [
                "na"
              ],
              "status": "recruiting",
              "conditions": [
                "Obesity and Metabolic Syndrome"
              ],
              "enrollment": {
                "type": "estimated",
                "count": 120
              },
              "start_date": {
                "date": "2026-03-31",
                "precision": "day"
              },
              "study_type": "interventional",
              "has_results": false,
              "first_posted": {
                "date": "2026-05-15",
                "precision": "day"
              },
              "last_updated": {
                "date": "2026-05-15",
                "precision": "day"
              },
              "lead_sponsor": "Tri-Service General Hospital (TSGH)",
              "interventions": [
                {
                  "name": "Tirzepatide with lifestyle modification",
                  "type": "drug"
                },
                {
                  "name": "Semaglutide with lifestyle modification",
                  "type": "drug"
                }
              ],
              "official_title": "Comparative Adipose Tissue and Cardiometabolic System Remodeling by Tirzepatide and Semaglutide: an AI-integrated Multimodal Metabolomics and Translational Mechanistic Study",
              "completion_date": {
                "date": "2029-09-30",
                "precision": "day"
              },
              "primary_completion_date": {
                "date": "2028-09-30",
                "precision": "day"
              }
            }
          ],
          "modified": true,
          "condition": "",
          "intervention": "",
          "next_page_token": "ZVNj7o2Elu8o3lpzW96v4q2tmpOQJJxsZvOl1PcW"
        }
      }
    },
    "tags": [
      "clinical-trials",
      "clinicaltrials-gov",
      "trial-search",
      "medical-research",
      "drug-development"
    ],
    "schema": {
      "type": "object",
      "$schema": "https://json-schema.org/draft/2020-12/schema",
      "required": [
        "input"
      ],
      "properties": {
        "input": {
          "type": "object",
          "required": [
            "type",
            "method"
          ],
          "properties": {
            "type": {
              "type": "string",
              "const": "http"
            },
            "method": {
              "enum": [
                "GET"
              ],
              "type": "string"
            },
            "queryParams": {
              "type": "object",
              "required": [
                "query"
              ],
              "properties": {
                "limit": {
                  "type": "integer",
                  "default": 10,
                  "maximum": 50,
                  "minimum": 1
                },
                "phase": {
                  "enum": [
                    "early1",
                    "1",
                    "2",
                    "3",
                    "4",
                    "na"
                  ],
                  "type": "string",
                  "description": "early1 = early phase 1; na = not applicable"
                },
                "query": {
                  "type": "string",
                  "maxLength": 200,
                  "description": "Free-text search over all study fields"
                },
                "status": {
                  "type": "string",
                  "maxLength": 200,
                  "description": "Comma-separated, up to 5 of: recruiting, not_yet_recruiting, active_not_recruiting, enrolling_by_invitation, completed, suspended, terminated, withdrawn, available, no_longer_available, temporarily_not_available, approved_for_marketing, withheld, unknown"
                },
                "sponsor": {
                  "type": "string",
                  "maxLength": 200,
                  "description": "Lead sponsor name filter"
                },
                "condition": {
                  "type": "string",
                  "maxLength": 200,
                  "description": "Condition or disease filter"
                },
                "page_token": {
                  "type": "string",
                  "maxLength": 512,
                  "description": "next_page_token of the previous page"
                },
                "intervention": {
                  "type": "string",
                  "maxLength": 200,
                  "description": "Intervention or treatment filter"
                }
              },
              "additionalProperties": false
            }
          },
          "additionalProperties": false
        },
        "output": {
          "type": "object",
          "required": [
            "type"
          ],
          "properties": {
            "type": {
              "type": "string"
            },
            "example": {
              "type": "object",
              "required": [
                "as_of",
                "source",
                "caveat",
                "modified",
                "query",
                "condition",
                "intervention",
                "sponsor",
                "status",
                "phase",
                "count",
                "total",
                "studies",
                "next_page_token"
              ],
              "properties": {
                "note": {
                  "type": "string",
                  "description": "Present only on a sample or empty response"
                },
                "as_of": {
                  "type": "string",
                  "format": "date-time",
                  "description": "Retrieval time, UTC"
                },
                "count": {
                  "type": "integer",
                  "description": "Studies on this page"
                },
                "phase": {
                  "type": "string",
                  "description": "Applied phase filter; empty when none"
                },
                "query": {
                  "type": "string"
                },
                "total": {
                  "type": "integer",
                  "description": "Studies matching across all pages"
                },
                "caveat": {
                  "type": "string",
                  "description": "Fixed interpretation note"
                },
                "source": {
                  "type": "object",
                  "required": [
                    "name",
                    "url",
                    "citation"
                  ],
                  "properties": {
                    "url": {
                      "type": "string"
                    },
                    "name": {
                      "type": "string"
                    },
                    "citation": {
                      "type": "string",
                      "description": "Attribution requested by the registry"
                    }
                  },
                  "additionalProperties": false
                },
                "status": {
                  "type": "array",
                  "items": {
                    "type": "string"
                  },
                  "description": "Applied status filter"
                },
                "sponsor": {
                  "type": "string",
                  "description": "Applied filter; empty when none"
                },
                "studies": {
                  "type": "array",
                  "items": {
                    "type": "object"
                  },
                  "description": "Study summaries: nct_id, title, official_title, status (lowercase registry status), study_type, phases[] (early1|1|2|3|4|na), conditions[], interventions[] {type, name}, lead_sponsor, start_date/primary_completion_date/completion_date {date, precision: day|month|year, type?} (absent when not reported), enrollment {count, type}, has_results, url"
                },
                "modified": {
                  "type": "boolean",
                  "description": "Always true: fields are normalized, not the registry's verbatim record"
                },
                "condition": {
                  "type": "string",
                  "description": "Applied filter; empty when none"
                },
                "intervention": {
                  "type": "string",
                  "description": "Applied filter; empty when none"
                },
                "next_page_token": {
                  "type": "string",
                  "description": "Pass as page_token for the next page; empty on the last page"
                }
              },
              "additionalProperties": false
            }
          }
        }
      }
    },
    "category": "health"
  }
}

Provenance

Seen in the source catalog
2026-10-20 21:12Z
Last indexed by Roundhouse
2026-10-24 11:00Z
Last enriched (probe, favicon, geo)
2026-10-20 21:45Z
x402 version
2
Max timeout
300s
Liveness probe
HTTP 402
Report

Hand this page to an agent

Copy the prompt and paste it into Claude, an MCP client or your own agent — it will vet this service and call it over the free read API. No key, no account.

GET api.roundhouseai.io/v0/endpoints

This endpoint's own trailing-30-day call count, as published by the upstream catalog and snapshotted daily. 5 snapshots so far. Verified volume counts only settlements with an on-chain EIP-3009 marker.

Open skill.md
Show the prompt
Using Roundhouse, look up the x402 service Clinical Trial Search and tell me whether it is
worth paying: what a call costs, whether the endpoint answered when last probed, and what
its payment record actually shows.

curl -s 'https://api.roundhouseai.io/v0/endpoints?q=Clinical%20Trial%20Search'
curl -s 'https://api.roundhouseai.io/v0/merchants/<the payTo wallet returned above>'

Then call it: read the price from the live 402 at https://clinical-trials.use.x402atlas.com/search, never from
a cached figure, and pay with an x402 client.

The /v0 API needs an API key (`authorization: Bearer rh_live_…`) on everything except
/v0/unified* and /v0/endpoints. Either pay over x402 (mint a personal key for $0.01 at
GET https://api.roundhouseai.io/v0/test/x402), or ask me for an organization key, which I create at
https://roundhouseai.io/dashboard/connections. If you have neither, ask before going further.

If you do not have Roundhouse tools or skills installed, read
https://roundhouseai.io/skill.md first — it is the whole procedure.