ClinicalIntelPulse

FDA/EMA drug approval probability + PDUFA calendar for a disease area — which Phase 3 drugs are most likely to win approval in 12-24 months, with mechanism, trial results, approval-probability scores and historical phase-3 success rates. Worldwide. For biotech-investing and payer agents.

DataLiveeip155:8453Exactvia cdp
Fda-approvalPdufaEmaPhase-3Drug-approval
Settlements · 30d
641↑ 487%
No per-endpoint history for this service yet, so this is payments indexed to its PROVIDER's wallet over 30 days.
$768.65
Verified settled volume
A floor: summed over 5,000 of 11,315 verified settlements.
$0.250
Listed price
As published in the catalog. Always read the live 402 before paying.
1
Calls · 30d
Upstream's own call count for this endpoint, not ours.
1
Unique payers · 30d
Last called 2026-07-01 04:24Z
—
Upstream on-chain volume
Reported by the source catalog.
Paid to
0x50ab2018c06c6E4eAA9BA52057Eb55eD284912fc

The wallet the 402 directs payment to. Its whole payment record — every payer, every chain — is on the merchant page.

Asset 0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913

Provider

The payTo wallet does not resolve to a registered ERC-8004 agent. That is not a verdict on the service — most of the catalog is unregistered.

Live 402 challenge

Captured by the enrichment pass, not read just now. Prices can change — always read the 402 the endpoint answers with.

{
  "error": "X-PAYMENT header is required",
  "accepts": [
    {
      "asset": "0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913",
      "extra": {
        "name": "USD Coin",
        "version": "2"
      },
      "payTo": "0x50ab2018c06c6E4eAA9BA52057Eb55eD284912fc",
      "scheme": "exact",
      "network": "base",
      "mimeType": "application/json",
      "resource": "https://clinicalintelpulse.theaslangroupllc.com/api/clinical/approval-outlook",
      "description": "FDA/EMA drug approval probability + PDUFA calendar for a disease area — which Phase 3 drugs are most likely to win approval in 12-24 months, with mechanism, trial results, approval-probability scores and historical phase-3 success rates. Worldwide. For biotech-investing and payer agents.",
      "maxAmountRequired": "250000",
      "maxTimeoutSeconds": 300
    }
  ],
  "x402Version": 1
}

Accepts

The payment requirements as published to the catalog. Read the live 402 before paying — a price here is a claim, not a quote.

0.25USDC≈ $0.25 USD
on Base · exact scheme

Pay 0.25 USDC on Base to 0x50ab…912fc. The signed payment is good for 5 minutes.

USD Coin contract
0x8335…02913
Payment window
5 minutes
As published
250000 smallest units
250000units
on solana:5eykt4UsFv8P8NJdTREpY1vzqKqZKvdp · exact scheme

That figure is in the token’s smallest units. Roundhouse does not hold this contract’s decimals, so it is shown as published rather than converted.

Token contract
EPjFWd…TDt1v
Payment window
5 minutes
The catalog’s raw entry
[
  {
    "asset": "0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913",
    "extra": {
      "name": "USD Coin",
      "version": "2"
    },
    "payTo": "0x50ab2018c06c6E4eAA9BA52057Eb55eD284912fc",
    "amount": "250000",
    "scheme": "exact",
    "network": "eip155:8453",
    "maxTimeoutSeconds": 300
  },
  {
    "asset": "EPjFWdd5AufqSSqeM2qN1xzybapC8G4wEGGkZwyTDt1v",
    "extra": {
      "feePayer": "BFK9TLC3edb13K6v4YyH3DwPb5DSUpkWvb7XnqCL9b4F"
    },
    "payTo": "985iFjbnGQ3dJcwXnfRCMSrH4Jnc3kW1N6msR64B5KX1",
    "amount": "250000",
    "scheme": "exact",
    "network": "solana:5eykt4UsFv8P8NJdTREpY1vzqKqZKvdp",
    "maxTimeoutSeconds": 300
  }
]

Extensions

{
  "bazaar": {
    "info": {
      "input": {
        "type": "http",
        "method": "GET",
        "queryParams": {
          "lang": "en | es | fr | de | ja | zh | ko | pt | ar | hi (default: en)",
          "agency": "FDA | EMA | both (default: both)",
          "horizon": "12m | 18m | 24m (default: 18m)",
          "condition": "Disease area — e.g. \"Alzheimer Disease\" | \"Multiple Myeloma\" | \"NASH\" | \"Heart Failure\" | \"Obesity\""
        }
      },
      "output": {
        "type": "json",
        "example": {
          "query_summary": {
            "horizon": "18m",
            "agencies": [
              "FDA",
              "EMA"
            ],
            "condition": "Alzheimer Disease"
          },
          "market_context": "Alzheimer's is the highest-value CNS approval category. Any successful amyloid or tau therapy represents $5-15B peak sales potential.",
          "pdufa_calendar": [
            {
              "drug": "Donanemab",
              "sponsor": "Eli Lilly",
              "indication": "Early symptomatic AD",
              "pdufa_date": "2025-Q2",
              "priority_review": true
            }
          ],
          "approval_candidates": [
            {
              "drug": "Lecanemab (Leqembi)",
              "nctId": "NCT03887455",
              "sponsor": "Eisai / Biogen",
              "key_risk": "ARIA (amyloid-related imaging abnormalities) safety profile limiting real-world use",
              "mechanism": "Anti-amyloid monoclonal antibody (protofibrils)",
              "ema_status": "CHMP assessment ongoing 2025",
              "fda_status": "Full approval received 2023; expanded label applications pending",
              "trial_result": "Positive — 27% slowing of clinical decline vs placebo (p<0.001)",
              "approval_probability": 85
            }
          ],
          "approval_rate_context": {
            "rare_disease_premium": "Breakthrough therapy designation adds ~15% probability uplift",
            "us_approval_rate_phase3_pct": 58,
            "disease_area_historical_phase3_success_pct": 55
          }
        }
      }
    },
    "schema": {
      "type": "object",
      "$schema": "https://json-schema.org/draft/2020-12/schema"
    }
  },
  "builder-code": {
    "info": {
      "a": "bc_gxy6qn5p"
    },
    "schema": {
      "type": "object",
      "$schema": "https://json-schema.org/draft/2020-12/schema",
      "properties": {
        "a": {
          "type": "string",
          "pattern": "^[a-z0-9_]{1,32}$",
          "description": "App builder code"
        },
        "s": {
          "type": "array",
          "items": {
            "type": "string",
            "pattern": "^[a-z0-9_]{1,32}$"
          },
          "description": "Service builder codes"
        },
        "w": {
          "type": "string",
          "pattern": "^[a-z0-9_]{1,32}$",
          "description": "Wallet builder code"
        }
      },
      "additionalProperties": false
    }
  }
}

Provenance

Seen in the source catalog
2026-07-01 04:24Z
Last indexed by Roundhouse
2026-07-30 16:00Z
Last enriched (probe, favicon, geo)
2026-09-11 09:45Z
x402 version
2
Max timeout
300s
Liveness probe
HTTP 402
Report

Hand this page to an agent

Copy the prompt and paste it into Claude, an MCP client or your own agent — it will vet this service and call it over the free read API. No key, no account.

GET api.roundhouseai.io/v0/endpoints

No per-endpoint history for this service yet, so this is payments indexed to its PROVIDER's wallet over 30 days. Verified volume counts only settlements with an on-chain EIP-3009 marker.

Open skill.md
Show the prompt
Using Roundhouse, look up the x402 service ClinicalIntelPulse and tell me whether it is
worth paying: what a call costs, whether the endpoint answered when last probed, and what
its payment record actually shows.

curl -s 'https://api.roundhouseai.io/v0/endpoints?q=ClinicalIntelPulse'
curl -s 'https://api.roundhouseai.io/v0/merchants/<the payTo wallet returned above>'

Then call it: read the price from the live 402 at https://clinicalintelpulse.vercel.app/api/clinical/approval-outlook, never from
a cached figure, and pay with an x402 client.

The /v0 API needs an API key (`authorization: Bearer rh_live_…`) on everything except
/v0/unified* and /v0/endpoints. Mint a personal key for $0.01 at GET https://api.roundhouseai.io/v0/test/x402,
or use an organization key from https://roundhouseai.io/dashboard/team.

If you do not have Roundhouse tools or skills installed, read
https://roundhouseai.io/skill.md first — it is the whole procedure.